G
Ge Zhou
Researcher at University of Texas Southwestern Medical Center
Publications - 5
Citations - 653
Ge Zhou is an academic researcher from University of Texas Southwestern Medical Center. The author has contributed to research in topics: Proteomics & Carcinogenesis. The author has an hindex of 4, co-authored 5 publications receiving 645 citations.
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Journal ArticleDOI
2D Differential In-gel Electrophoresis for the Identification of Esophageal Scans Cell Cancer-specific Protein Markers
Ge Zhou,Hongmei Li,Dianne L. DeCamp,She Chen,Hongjun Shu,Yi Gong,Michael J. Flaig,John W. Gillespie,Nan Hu,Philip R. Taylor,Michael R. Emmert-Buck,Lance A. Liotta,Emanuel F. Petricoin,Yingming Zhao +13 more
TL;DR: Global quantification of protein expression between laser capture microdissection-microdissected patient-matched cancer cells and normal cells using 2D DIGE in combination with mass spectrometry is a powerful tool for the molecular characterization of cancer progression and identification of cancer-specific protein markers.
Journal ArticleDOI
Proteomic analysis of human prostate cancer.
Mamoun Ahram,Carolyn J.M. Best,Michael J. Flaig,John W. Gillespie,Isabel M. Leiva,Rodrigo F. Chuaqui,Ge Zhou,Hungjun Shu,Paul H. Duray,W. Marston Linehan,Mark Raffeld,David K. Ornstein,Yingming Zhao,Emanuel F. Petricoin,Michael R. Emmert-Buck +14 more
TL;DR: In this article, cellular proteomes of matched normal prostate epithelial cells and high grade prostate cancer cells were analyzed by tissue microdissection, two-dimensional electrophoresis, and mass spectrometry.
Journal ArticleDOI
Affinity enrichment of plasma membrane for proteomics analysis.
TL;DR: An affinity enrichment method is described, which combines cell surface biotinylation with affinity enrichment by immobilized streptavidin beads, for the isolation of plasma membranes, which results in a 400‐fold enrichment of plasma membrane relative to endoplasmic reticulum.
Journal ArticleDOI
Proteomic analysis of global alteration of protein expression in squamous cell carcinoma of the esophagus.
TL;DR: Proteomics strategy applied to quantify proteins differentially expressed in ESCC shed new insights on the mechanism of tumorigenesis and provide candidate biomarkers for early detection of ESCC.