G
Gen Zou
Researcher at Chinese Academy of Sciences
Publications - 44
Citations - 1589
Gen Zou is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Trichoderma reesei & Biology. The author has an hindex of 15, co-authored 32 publications receiving 1178 citations. Previous affiliations of Gen Zou include Shanghai Normal University & Zhejiang University.
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Efficient genome editing in filamentous fungus Trichoderma reesei using the CRISPR/Cas9 system.
TL;DR: The results illustrate that the CRISPR/Cas9 system is a powerful genome-manipulating tool for T. reesei and most likely for other filamentous fungal species, which may accelerate studies on functional genomics and strain improvement in these filamentous fungi.
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Genomic and secretomic analyses reveal unique features of the lignocellulolytic enzyme system of Penicillium decumbens.
Guodong Liu,Lei Zhang,Xiaomin Wei,Gen Zou,Yuqi Qin,Liang Ma,Jie Li,Huajun Zheng,Shengyue Wang,Chengshu Wang,Luying Xun,Luying Xun,Guoping Zhao,Guoping Zhao,Zhihua Zhou,Yinbo Qu +15 more
TL;DR: Comparative genomics analysis with the phylogenetically most similar species Penicillium chrysogenum and proteomic analysis of secretomes revealed that P. decumbens has evolved with more genes involved in plant cell wall degradation, but fewer genes in cellular metabolism and regulation.
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Improvement of cellulase activity in Trichoderma reesei by heterologous expression of a beta-glucosidase gene from Penicillium decumbens.
TL;DR: The results indicated that the heterologous expression of a beta-glucosidase gene in T. reesei might produce balanced cellulase preparation.
Journal ArticleDOI
Construction of a cellulase hyper-expression system in Trichoderma reesei by promoter and enzyme engineering
Gen Zou,Shaohua Shi,Yanping Jiang,Joost van den Brink,Ronald P. de Vries,Ling Chen,Jun Zhang,Liang Ma,Chengshu Wang,Zhihua Zhou +9 more
TL;DR: This study shows that optimizations of the promoter and linker for hybrid genes can dramatically improve the efficiency of heterologous expression of cellulase genes in T. reesei.
Journal ArticleDOI
Long-term strain improvements accumulate mutations in regulatory elements responsible for hyper-production of cellulolytic enzymes.
Guodong Liu,Lei Zhang,Yuqi Qin,Gen Zou,Zhonghai Li,Xing Yan,Xiaomin Wei,Mei Chen,Ling Chen,Kai Zheng,Jun Zhang,Liang Ma,Jie Li,Rui Liu,Hai Xu,Xiaoming Bao,Xu Fang,Lushan Wang,Yaohua Zhong,Weifeng Liu,Huajun Zheng,Shengyue Wang,Chengshu Wang,Luying Xun,Luying Xun,Guoping Zhao,Guoping Zhao,Tianhong Wang,Zhihua Zhou,Yinbo Qu +29 more
TL;DR: In this article, the genome of the hyper-producer P. decumbens JU-A10-T was sequenced and compared with that of the wild-type strain 114-2.