S
Shengyue Wang
Researcher at Chinese National Human Genome Center
Publications - 99
Citations - 11379
Shengyue Wang is an academic researcher from Chinese National Human Genome Center. The author has contributed to research in topics: Gene & Genome. The author has an hindex of 46, co-authored 95 publications receiving 10144 citations. Previous affiliations of Shengyue Wang include Fudan University & Shanghai Jiao Tong University.
Papers
More filters
Journal ArticleDOI
Symbiotic gut microbes modulate human metabolic phenotypes
Min Li,Baohong Wang,Menghui Zhang,Mattias Rantalainen,Shengyue Wang,Haokui Zhou,Yan Zhang,Jian Shen,Xiaoyan Pang,Meiling Zhang,Hua Wei,Yu Chen,Haifeng Lu,Jian Zuo,Mingming Su,Yunping Qiu,Wei Jia,Chaoni Xiao,Leon M. Smith,Shengli Yang,Elaine Holmes,Huiru Tang,Guoping Zhao,Jeremy K. Nicholson,Lanjuan Li,Liping Zhao +25 more
TL;DR: The approach for understanding the dynamic basis of host–microbiome symbiosis provides a foundation for the development of functional metagenomics as a probe of systemic effects of drugs and diet that are of relevance to personal and public health care solutions.
Journal ArticleDOI
Interactions between gut microbiota, host genetics and diet relevant to development of metabolic syndromes in mice
Chenhong Zhang,Menghui Zhang,Shengyue Wang,Ruijun Han,Youfang Cao,Weiying Hua,Yuejian Mao,Xiaojun Zhang,Xiaoyan Pang,Chaochun Wei,Guoping Zhao,Yan（陈雁） Chen,Liping Zhao +12 more
TL;DR: Diet has a dominating role in shaping gut microbiota and changes of some key populations may transform the gut microbiota of Wt animals into a pathogen-like entity relevant to development of MS, despite a complete host genome.
Journal ArticleDOI
Molecular Evolution of the SARS Coronavirus, during the Course of the SARS Epidemic in China
Jian Feng He,Guo Wen Peng,Jun Min,De Wen Yu,Wen Jia Liang,Shuyi Zhang,Rui Heng Xu,Huan Ying Zheng,Xin Wei Wu,Jun Xu,Zhan Hui Wang,Ling Fang,Xin Zhang,Hui Li,Xin Ge Yan,Jiahai Lu,Zhihong Hu,Ji Cheng Huang,Zhuo Yue Wan,Jin Lin Hou,Jin Yan Lin,Huai Dong Song,Shengyue Wang,Xiang Jun Zhou,Guo Wei Zhang,Bo Wei Gu,Huajun Zheng,Xiang Lin Zhang,Mei He,Kui Zheng,Bo Fei Wang,Gang Fu,Xiao Ning Wang,Sai Juan Chen,Zhu Chen,Zhu Chen,Pei Hao,Hua Tang,Shuang Xi Ren,Yang Zhong,Zong Ming Guo,Qi Liu,You Gang Miao,Xiangyin Kong,Wei Zhong He,Yixue Li,Chung-I Wu,Guoping Zhao,Rossa W.K. Chiu,Stephen S.C. Chim,Yu K. Tong,Paul K.S. Chan,John S. Tam,Y.M. Dennis Lo +53 more
TL;DR: The spike protein showed the strongest initial responses to positive selection pressures, followed by subsequent purifying selection and eventual stabilization, and major deletions were observed in the Orf8 region of the genome at the start and the end of the epidemic.
Journal ArticleDOI
Cross-host evolution of severe acute respiratory syndrome coronavirus in palm civet and human
Huai-Dong Song,Chang-Chun Tu,Guo-Wei Zhang,Shengyue Wang,Kui Zheng,Lian-Cheng Lei,Qiu-Xia Chen,Yu-Wei Gao,Hui-Qiong Zhou,Hua Xiang,Hua-Jun Zheng,Shur-Wern Wang Chern,Feng Cheng,Chun-Ming Pan,Hua Xuan,Sai-Juan Chen,Hui-Ming Luo,Duan-Hua Zhou,Yu-Fei Liu,Jian-Feng He,Peng-Zhe Qin,Ling-Hui Li,Yu-Qi Ren,Wen-Jia Liang,Ye-Dong Yu,Larry J. Anderson,Ming Wang,Rui-Heng Xu,Xin-Wei Wu,Huan-Ying Zheng,Jin-Ding Chen,Guodong Liang,Yang Gao,Ming Liao,Ling Fang,Li-Yun Jiang,Hui Li,Fang Chen,Biao Di,Li-Juan He,Jin-Yan Lin,Suxiang Tong,Xiangang Kong,Lin Du,Pei Hao,Hua Tang,Andrea Bernini,Xiao-Jing Yu,Ottavia Spiga,Zong-Ming Guo,Hai-Yan Pan,Wei-Zhong He,Jean-Claude Manuguerra,Arnaud Fontanet,Antoine Danchin,Neri Niccolai,Yixue Li,Chung-I Wu,Guoping Zhao +58 more
TL;DR: The ratio of nonsynonymous/synonymous nucleotide substitution in palm civets collected 1 yr apart from different geographic locations is very high, suggesting a rapid evolving process of viral proteins in civet as well, much like their adaptation in the human host in the early 2002-2003 epidemic.
Journal ArticleDOI
The Schistosoma japonicum genome reveals features of host-parasite interplay
Yan Zhou,Huajun Zheng,Yangyi Chen,Lei Zhang,Kai Wang,Jing Guo,Zhen Huang,Bo Zhang,Wei Huang,Ke Jin,Tonghai Dou,Masami Hasegawa,Li Wang,Yuan Zhang,Jie Zhou,Lin Tao,Zhiwei Cao,Yixue Li,Tomas Vinar,Brona Brejová,Daniel G. Brown,Ming Li,David J. Miller,David Blair,Yang Zhong,Zhu Chen,Feng Liu,Wei Hu,Zhi-Qin Wang,Qin-Hua Zhang,Huai-Dong Song,Sai-Juan Chen,Xue-Nian Xu,Bin Xu,Chuan Ju,Yucheng Huang,Paul J. Brindley,Donald P. McManus,Zheng Feng,Ze-Guang Han,Gang Lu,Shuang-Xi Ren,Y.S. Wang,Wenyi Gu,Hui Kang,Jie Chen,Xiaoyun Chen,Shuting Chen,Lijun Wang,Jie Yan,Biyun Wang,Xinyan Lv,Lei Jin,Bofei Wang,Shiyin Pu,Xiang-Lin Zhang,Wei Zhang,Qiuping Hu,Genfeng Zhu,Jun Wang,Jun Yu,Jing Wang,Huanming Yang,Zemin Ning,Matthew Beriman,Chia-Lin Wei,Yijun Ruan,Guoping Zhao,Shengyue Wang +68 more
TL;DR: The genome provides a global insight into the molecular architecture and host interaction of this complex metazoan pathogen, revealing that it can exploit host nutrients, neuroendocrine hormones and signalling pathways for growth, development and maturation.