G
Geoffrey C. Gurtner
Researcher at Stanford University
Publications - 478
Citations - 32002
Geoffrey C. Gurtner is an academic researcher from Stanford University. The author has contributed to research in topics: Wound healing & Medicine. The author has an hindex of 76, co-authored 423 publications receiving 25985 citations. Previous affiliations of Geoffrey C. Gurtner include Duke University & York University.
Papers
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Journal ArticleDOI
Db/db mice exhibit severe wound-healing impairments compared with other murine diabetic strains in a silicone-splinted excisional wound model
Joseph Michaels,Samara S. Churgin,Keith M. Blechman,Matthew R. Greives,Shahram Aarabi,Robert D. Galiano,Geoffrey C. Gurtner +6 more
TL;DR: The results suggest that splinted db/db mice may be the most appropriate model for studying diabetic wound‐healing interventions as they demonstrate the most significant impairment in wound healing.
Immunotargeting of liposomes to activated vascular endothelial cells: A strategy for site-selective delivery in the cardiovascular system (cytokine activationydrug deliveryyE-selectinyimmunoliposomeyvascular endothelium)
David D. Spragg,D Ennis R. Alford,R Uth Greferath,C Harles E. Larsen,K Yung-Dall Lee,Geoffrey C. Gurtner,Myron I. Cybulsky,P. Francois Tosi,C Laude Nicolau,Michael A. Gimbrone +9 more
TL;DR: In this paper, E-selectin, an endothelial-specific cell surface molecule expressed at sites of activation in vivo and inducible in cultured human umbilical vein endothelial cells (HUVEC) by treatment with cytokines such as recombinant human interleukin 1b (IL-1b).
Journal ArticleDOI
Pushing Back: Wound Mechanotransduction in Repair and Regeneration
TL;DR: An improved understanding of these interactions will facilitate the development of novel biophysical materials and mechanomodulatory approaches to augment wound repair and regeneration.
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Preventing Engrailed-1 activation in fibroblasts yields wound regeneration without scarring
Shamik Mascharak,Heather E. desJardins-Park,Michael F. Davitt,Michelle Griffin,Mimi R. Borrelli,Alessandra L. Moore,Kellen Chen,Bryan Duoto,Malini Chinta,Deshka S. Foster,Abra H. Shen,Michael Januszyk,Sun Hyung Kwon,Gerlinde Wernig,Derrick C. Wan,H. Peter Lorenz,Geoffrey C. Gurtner,Michael T. Longaker +17 more
TL;DR: In this paper, the authors identify a dermal ENF subpopulation that gives rise to postnatally derived EPFs by activating Engrailed-1 expression during adult wound healing.
Journal ArticleDOI
Hypoxia-Induced Mediators of Stem/Progenitor Cell Trafficking Are Increased in Children With Hemangioma
Mark E. Kleinman,Matthew R. Greives,Samara S. Churgin,Keith M. Blechman,Eric I. Chang,Daniel J. Ceradini,Oren M. Tepper,Geoffrey C. Gurtner +7 more
TL;DR: Findings demonstrate that proliferating hemangiomas express known mediators of vasculogenesis and suggest that this process may play a role in the initiation or progression of this disease.