G
Geoffrey C. Gurtner
Researcher at Stanford University
Publications - 478
Citations - 32002
Geoffrey C. Gurtner is an academic researcher from Stanford University. The author has contributed to research in topics: Wound healing & Medicine. The author has an hindex of 76, co-authored 423 publications receiving 25985 citations. Previous affiliations of Geoffrey C. Gurtner include Duke University & York University.
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Journal ArticleDOI
Adult vasculogenesis occurs through in situ recruitment, proliferation, and tubulization of circulating bone marrow-derived cells
Oren M. Tepper,Jennifer M. Capla,Robert D. Galiano,Daniel J. Ceradini,Matthew J. Callaghan,Mark E. Kleinman,Geoffrey C. Gurtner +6 more
TL;DR: It is concluded that BM-derived cells produce new blood vessels via localized recruitment, proliferation, and differentiation of circulating cells in a sequence of events markedly different from existing paradigms of angiogenesis.
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Focal adhesion kinase links mechanical force to skin fibrosis via inflammatory signaling.
Victor W. Wong,Kristine C. Rustad,Satoshi Akaishi,Michael Sorkin,Jason P. Glotzbach,Michael Januszyk,Emily R. Nelson,Kemal Levi,Josemaria Paterno,Ivan N. Vial,Anna A. Kuang,Michael T. Longaker,Geoffrey C. Gurtner +12 more
TL;DR: It is reported that physical force regulates fibrosis through inflammatory FAK–ERK–MCP-1 pathways and that molecular strategies targeting FAK can effectively uncouple mechanical force from pathologic scar formation.
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Targeted disruption of the murine VCAM1 gene: essential role of VCAM-1 in chorioallantoic fusion and placentation.
Geoffrey C. Gurtner,Vannessa M. Davis,Hongmei Li,Michael J. McCoy,Arlene H. Sharpe,Myron I. Cybulsky +5 more
TL;DR: A novel role for VCAM-1 in the formation of the umbilical cord and placenta during development is reported and a role in early placental formation after chorioallantoic fusion was observed.
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The molecular basis for impaired hypoxia-induced VEGF expression in diabetic tissues
Hariharan Thangarajah,Dachun Yao,Edward I. Chang,Yubin Shi,Leila Jazayeri,Ivan N. Vial,Robert D. Galiano,Xue Liang Du,Raymon H. Grogan,Michael G. Galvez,Michael Januszyk,Michael Brownlee,Geoffrey C. Gurtner +12 more
TL;DR: Findings define molecular defects that underlie impaired VEGF production in diabetic tissues and offer a promising direction for therapeutic intervention.
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Enhancement of mesenchymal stem cell angiogenic capacity and stemness by a biomimetic hydrogel scaffold.
Kristine C. Rustad,Victor W. Wong,Michael Sorkin,Jason P. Glotzbach,Melanie R. Major,Jayakumar Rajadas,Michael T. Longaker,Geoffrey C. Gurtner +7 more
TL;DR: Wounds treated with MSC-seeded hydrogels demonstrated significantly enhanced angiogenesis, which was associated with increased levels of VEGF and other angiogenic cytokines within the wounds.