M
Michael Januszyk
Researcher at Stanford University
Publications - 140
Citations - 6137
Michael Januszyk is an academic researcher from Stanford University. The author has contributed to research in topics: Wound healing & Medicine. The author has an hindex of 35, co-authored 107 publications receiving 4305 citations. Previous affiliations of Michael Januszyk include University of Chicago.
Papers
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Journal ArticleDOI
Single-cell RNA-seq reveals ectopic and aberrant lung-resident cell populations in idiopathic pulmonary fibrosis.
Taylor Adams,Jonas C. Schupp,Sergio Poli,Ehab A. Ayaub,Nir Neumark,Farida Ahangari,Sarah G. Chu,Benjamin A. Raby,Benjamin A. Raby,Giuseppe DeIuliis,Michael Januszyk,Qiaonan Duan,Heather A. Arnett,Asim Siddiqui,George R. Washko,Robert J. Homer,Xiting Yan,Ivan O. Rosas,Naftali Kaminski +18 more
TL;DR: A single-cell atlas of idiopathic pulmonary fibrosis (IPF), a fatal interstitial lung disease, is provided by profiling 312,928 cells from 32 IPF, 28 smoker and nonsmoker controls, and 18 chronic obstructive pulmonary disease (COPD) lungs.
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Identification and isolation of a dermal lineage with intrinsic fibrogenic potential
Yuval Rinkevich,Graham G. Walmsley,Michael S. Hu,Zeshaan N. Maan,Aaron M. Newman,Micha Drukker,Michael Januszyk,Geoffrey W. Krampitz,Geoffrey C. Gurtner,H. Peter Lorenz,Irving L. Weissman,Michael T. Longaker +11 more
TL;DR: In this article, the authors reveal the presence of at least two fibroblast lineages in murine dorsal skin and identify CD26/DPP4 as a surface marker that allows isolation of this lineage.
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Focal adhesion kinase links mechanical force to skin fibrosis via inflammatory signaling.
Victor W. Wong,Kristine C. Rustad,Satoshi Akaishi,Michael Sorkin,Jason P. Glotzbach,Michael Januszyk,Emily R. Nelson,Kemal Levi,Josemaria Paterno,Ivan N. Vial,Anna A. Kuang,Michael T. Longaker,Geoffrey C. Gurtner +12 more
TL;DR: It is reported that physical force regulates fibrosis through inflammatory FAK–ERK–MCP-1 pathways and that molecular strategies targeting FAK can effectively uncouple mechanical force from pathologic scar formation.
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The molecular basis for impaired hypoxia-induced VEGF expression in diabetic tissues
Hariharan Thangarajah,Dachun Yao,Edward I. Chang,Yubin Shi,Leila Jazayeri,Ivan N. Vial,Robert D. Galiano,Xue Liang Du,Raymon H. Grogan,Michael G. Galvez,Michael Januszyk,Michael Brownlee,Geoffrey C. Gurtner +12 more
TL;DR: Findings define molecular defects that underlie impaired VEGF production in diabetic tissues and offer a promising direction for therapeutic intervention.
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Stem Cells in Wound Healing: The Future of Regenerative Medicine? A Mini-Review
Dominik Duscher,Janos A. Barrera,Victor W. Wong,Zeshaan N. Maan,Alexander J. Whittam,Michael Januszyk,Geoffrey C. Gurtner +6 more
TL;DR: Light is shed on challenges and recent advances surrounding stem cell therapies for wound healing and limitations for their clinical adoption are discussed.