G
George R. Buchanan
Researcher at University of Texas Southwestern Medical Center
Publications - 167
Citations - 11959
George R. Buchanan is an academic researcher from University of Texas Southwestern Medical Center. The author has contributed to research in topics: Anemia & Thrombocytopenic purpura. The author has an hindex of 51, co-authored 166 publications receiving 10834 citations. Previous affiliations of George R. Buchanan include University of Texas at Austin & University of Texas at Dallas.
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Journal ArticleDOI
Prophylaxis versus episodic treatment to prevent joint disease in boys with severe hemophilia.
Marilyn J. Manco-Johnson,Marilyn J. Manco-Johnson,Thomas C. Abshire,Amy D. Shapiro,Brenda Riske,Michele R. Hacker,Ray F. Kilcoyne,J. David Ingram,M L Manco-Johnson,Sharon Funk,Linda J. Jacobson,Leonard A. Valentino,W. Keith Hoots,George R. Buchanan,Donna DiMichele,Michael Recht,Deborah L Brown,Cindy A. Leissinger,Shirley Bleak,Alan R. Cohen,Prasad Mathew,Alison Matsunaga,Desiree Medeiros,Diane J. Nugent,Gregory Thomas,Alexis A. Thompson,Kevin McRedmond,J. Michael Soucie,Harlan Austin,Bruce L. Evatt +29 more
TL;DR: Prophylaxis with recombinant factor VIII can prevent joint damage and decrease the frequency of joint and other hemorrhages in young boys with severe hemophilia A.
Journal ArticleDOI
Management of Sickle Cell Disease: Summary of the 2014 Evidence-Based Report by Expert Panel Members
Barbara P. Yawn,George R. Buchanan,Araba Afenyi-Annan,Samir K. Ballas,Kathryn L. Hassell,Andra H. James,Lanetta B. Jordan,Sophie Lanzkron,Richard Lottenberg,William J. Savage,Paula Tanabe,Russell E. Ware,M. Hassan Murad,Jonathan C. Goldsmith,Jonathan C. Goldsmith,Eduardo Ortiz,Robinson Fulwood,Ann Horton,Joylene John-Sowah +18 more
TL;DR: Hydxyurea and transfusion therapy are strongly recommended for many individuals with SCD and many other recommendations are based on quality of evidence that is less than high due to the paucity of clinical trials regarding screening, management, and monitoring for individuals withSCD.
Journal ArticleDOI
Improved survival of children and adolescents with sickle cell disease
TL;DR: It is found that most children with SCD now survive the childhood years, but young adults who transition to adult medical care are at high risk for early death.
Journal ArticleDOI
Survival of children with sickle cell disease
TL;DR: In this article, the authors defined an inception cohort of newborns with sickle cell anemia (SS), sickle-beta degrees -thalassemia (S beta degrees ), sicklehemoglobin C disease (SC), or sickle beta(+)-threshold leucocytosis (Sbeta(+)) who were identified by newborn screening and followed for up to 18 years.
Journal ArticleDOI
Stable mixed hematopoietic chimerism after bone marrow transplantation for sickle cell anemia
Mark C. Walters,Melinda Patience,W Leisenring,Zora R. Rogers,Victor M. Aquino,George R. Buchanan,I. A.G. Roberts,A.M Yeager,Lewis L. Hsu,Thomas V. Adamkiewicz,Joanne Kurtzberg,Elliott Vichinsky,B Storer,R Storb,Keith M. Sullivan +14 more
TL;DR: Allograft recipients with stable mixed chimerism had Rb S levels similar to donor levels, and only 1 patient required a red blood cell transfusion beyond 90 days posttransplantation.