L
Linda J. Jacobson
Researcher at University of Colorado Denver
Publications - 48
Citations - 3431
Linda J. Jacobson is an academic researcher from University of Colorado Denver. The author has contributed to research in topics: Fibrinolysis & Protein S. The author has an hindex of 24, co-authored 48 publications receiving 3124 citations. Previous affiliations of Linda J. Jacobson include Children's Mercy Hospital & Medical College of Wisconsin.
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Journal ArticleDOI
Prophylaxis versus episodic treatment to prevent joint disease in boys with severe hemophilia.
Marilyn J. Manco-Johnson,Marilyn J. Manco-Johnson,Thomas C. Abshire,Amy D. Shapiro,Brenda Riske,Michele R. Hacker,Ray F. Kilcoyne,J. David Ingram,M L Manco-Johnson,Sharon Funk,Linda J. Jacobson,Leonard A. Valentino,W. Keith Hoots,George R. Buchanan,Donna DiMichele,Michael Recht,Deborah L Brown,Cindy A. Leissinger,Shirley Bleak,Alan R. Cohen,Prasad Mathew,Alison Matsunaga,Desiree Medeiros,Diane J. Nugent,Gregory Thomas,Alexis A. Thompson,Kevin McRedmond,J. Michael Soucie,Harlan Austin,Bruce L. Evatt +29 more
TL;DR: Prophylaxis with recombinant factor VIII can prevent joint damage and decrease the frequency of joint and other hemorrhages in young boys with severe hemophilia A.
Journal ArticleDOI
Neutralizing antibodies against adeno-associated virus examined prospectively in pediatric patients with hemophilia.
Chengwen Li,Nattee Narkbunnam,Nattee Narkbunnam,Richard Jude Samulski,Aravind Asokan,Genlin Hu,L. J. Jacobson,M. J. Manco-Johnson,Paul E. Monahan,Marilyn J. Manco-Johnson,Brenda Riske,Ray F. Kilcoyne,M L Manco-Johnson,Sharon Funk,Linda J. Jacobson,J. David Ingram,Thomas C. Abshire,Thomas C. Abshire,Amy D. Shapiro,Michele R. Hacker,Leonard A. Valentino,W. Keith Hoots,Deborah L Brown,George R. Buchanan,Donna DiMichele,Michael Recht,Cindy A. Leissinger,Shirley Bleak,Alan R. Cohen,Prasad Mathew,Alison Matsunaga,Desiree Medeiros,Diane J. Nugent,Gregory Thomas,Alexis A. Thompson,Kevin McRedmond,J. Michael Soucie,Harlan Austin,Bruce L. Evatt +38 more
TL;DR: The results may guide rational design of clinical trials using alternative AAV serotypes and suggest that younger patients who are given AAV gene therapy will benefit from the lower prevalence of NAbs.
Journal ArticleDOI
Lupus anticoagulant and protein S deficiency in children with postvaricella purpura fulminans or thrombosis
Marilyn J. Manco-Johnson,Rachelle Nuss,Nigel Key,Christopher L. Moertel,Linda J. Jacobson,Sandra J. Meech,Adriana Weinberg,Jerry B. Lefkowitz +7 more
TL;DR: A subset of children with varicella infection, some of whom are coinfected with streptococcus, are prone to development of a lupus anticoagulant and an autoantibody to protein S, which results in acquired free protein S deficiency, and are at risk of having life-threatening thrombotic events.
Journal ArticleDOI
A new euglobulin clot lysis assay for global fibrinolysis.
TL;DR: It cannot be said that any of the test parameters are better than lysis time in distinguishing between these normal physiologic states; the most significant contributor is fibrinogen.
Journal ArticleDOI
The varicella-autoantibody syndrome.
Cassandra Josephson,Rachelle Nuss,Rachelle Nuss,Linda J. Jacobson,Linda J. Jacobson,Michele R. Hacker,Michele R. Hacker,James Murphy,Adriana Weinberg,Adriana Weinberg,Marilyn J. Manco-Johnson,Marilyn J. Manco-Johnson +11 more
TL;DR: Transient antiphospholipid and coagulation protein autoantibodies were common with VZV infection, but were not predictive of thrombotic complications.