G
Georgia Kapatai
Researcher at Public Health England
Publications - 21
Citations - 1791
Georgia Kapatai is an academic researcher from Public Health England. The author has contributed to research in topics: Serotype & Outbreak. The author has an hindex of 12, co-authored 21 publications receiving 1474 citations. Previous affiliations of Georgia Kapatai include Heart of England NHS Foundation Trust.
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Journal ArticleDOI
Whole-genome sequencing to delineate Mycobacterium tuberculosis outbreaks: a retrospective observational study
Timothy M Walker,Camilla L. C. Ip,Ruth H. Harrell,Jason T. Evans,Georgia Kapatai,Martin Dedicoat,David W Eyre,Daniel J. Wilson,Peter M. Hawkey,Peter M. Hawkey,Derrick W. Crook,Julian Parkhill,David Harris,A. Sarah Walker,Rory Bowden,Philip Monk,E. Grace Smith,Tim E. A. Peto +17 more
TL;DR: The genetic diversity of related M tuberculosis strains in the UK Midlands is estimated and the technique could identify super-spreaders and predict the existence of undiagnosed cases, potentially leading to early treatment of infectious patients and their contacts.
Journal ArticleDOI
Whole-genome sequencing for prediction of Mycobacterium tuberculosis drug susceptibility and resistance: a retrospective cohort study.
Timothy M Walker,Thomas Kohl,Shaheed V. Omar,Jessica Hedge,Carlos del Ojo Elias,Phelim Bradley,Zamin Iqbal,Silke Feuerriegel,Katherine E. Niehaus,Daniel J. Wilson,David A. Clifton,Georgia Kapatai,Camilla L. C. Ip,Rory Bowden,Francis Drobniewski,Francis Drobniewski,Caroline Allix-Béguec,Cyril Gaudin,Julian Parkhill,Roland Diel,Philip Supply,Philip Supply,Derrick W. Crook,E. Grace Smith,A. Sarah Walker,Nazir Ahmed Ismail,Stefan Niemann,Tim E. A. Peto +27 more
TL;DR: A broad catalogue of genetic mutations enable data from whole-genome sequencing to be used clinically to predict drug resistance, drug susceptibility, or to identify drug phenotypes that cannot yet be genetically predicted.
Journal ArticleDOI
Whole genome sequencing of Streptococcus pneumoniae: development, evaluation and verification of targets for serogroup and serotype prediction using an automated pipeline
Georgia Kapatai,Carmen L. Sheppard,Ali Al-Shahib,David Litt,Anthony Underwood,Timothy G. Harrison,Norman K. Fry +6 more
TL;DR: A WGS-based serotyping method that can predict capsular type to serotype level for 89/94 serotypes and to serogroup level for the remaining four is developed, which could be integrated into routine typing workflows in reference laboratories, reducing the need for phenotypic immunological testing.
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Whole-Genome Sequencing and Epidemiological Analysis Do Not Provide Evidence for Cross-transmission of Mycobacterium abscessus in a Cohort of Pediatric Cystic Fibrosis Patients
Kathryn A. Harris,Anthony Underwood,D. Kenna,Anthony Brooks,Ema Kavaliunaite,Georgia Kapatai,Rediat Tewolde,Paul Aurora,Garth Dixon +8 more
TL;DR: It has not been able to demonstrate cross-transmission of Mycobacterium abscessus within the hospital, except between siblings who had intense contact in the home environment, unless between siblings whose contact was intense at home.
Journal ArticleDOI
Group B streptococcal disease in UK and Irish infants younger than 90 days, 2014–15: a prospective surveillance study
Catherine O'Sullivan,Theresa Lamagni,Darshana Patel,Androulla Efstratiou,Robert Cunney,Robert Cunney,Mary Meehan,Shamez N Ladhani,Arlene Reynolds,Ruth Campbell,Lorraine Doherty,Margaret Boyle,Georgia Kapatai,Victoria J. Chalker,Diane S. J. Lindsay,Andrew Smith,Andrew Smith,Eleri Davies,Christine E. Jones,Christine E. Jones,Paul T. Heath +20 more
TL;DR: The incidence of invasive infant group B streptococcal disease in the UK and Ireland has increased since a comparable study done in 2000-01 and the burden of early-onset disease has not declined despite the introduction of national prevention guidelines.