G
Gerald T. Ankley
Researcher at United States Environmental Protection Agency
Publications - 374
Citations - 27860
Gerald T. Ankley is an academic researcher from United States Environmental Protection Agency. The author has contributed to research in topics: Vitellogenin & Pimephales promelas. The author has an hindex of 82, co-authored 356 publications receiving 25514 citations. Previous affiliations of Gerald T. Ankley include Michigan State University & Pacific Northwest National Laboratory.
Papers
More filters
Journal ArticleDOI
Comparison of fathead minnow ovary explant and H295R cell-based steroidogenesis assays for identifying endocrine-active chemicals.
Daniel L. Villeneuve,Gerald T. Ankley,Elizabeth A. Makynen,Lindsey S. Blake,Katie J. Greene,Eric Higley,John L. Newsted,John P. Giesy,John P. Giesy,John P. Giesy,Markus Hecker +10 more
TL;DR: In this article, the utility of the H295R assay for predicting effects and/or understanding mechanisms of action across species and tissues was investigated for detecting endocrine active chemicals capable of modulating steroid hormone synthesis.
Journal ArticleDOI
Predicting chronic toxicity of sediments spiked with zinc: An evaluation of the acid-volatile sulfide model using a life-cycle test with the midge Chironomus tentans
TL;DR: The chemical and biological data from this study compare favorably with observations made in short-term exposures and thus support the use of AVS as a normalization phase for predicting toxicity in metal-contaminated sediments.
Journal ArticleDOI
A QSAR evaluation of Ah receptor binding of halogenated aromatic xenobiotics.
TL;DR: This study evaluated the use of structural conformations other than those of minimum energy for the purpose of developing a model for AhR binding affinity that encompasses more of the halogenated aromatic chemicals known to interact with the receptor.
Journal ArticleDOI
Identifying toxicants: NETAC's toxicity-based approach
Journal ArticleDOI
Propiconazole Inhibits Steroidogenesis and Reproduction in the Fathead Minnow (Pimephales promelas)
Sarah Y. Skolness,Chad A. Blanksma,Jenna E. Cavallin,Jessica J. Churchill,Elizabeth J. Durhan,Kathleen M. Jensen,Rodney D. Johnson,Michael D. Kahl,Elizabeth A. Makynen,Daniel L. Villeneuve,Gerald T. Ankley +10 more
TL;DR: This study provides important data relative to the potential endocrine activity of propiconazole in fish and, more generally, to the further delineation of pathways for the reproductive effects of steroid synthesis inhibitors in fish.