G
Geraldine L.C. Paulus
Researcher at Massachusetts Institute of Technology
Publications - 21
Citations - 2101
Geraldine L.C. Paulus is an academic researcher from Massachusetts Institute of Technology. The author has contributed to research in topics: Graphene & Carbon nanotube. The author has an hindex of 16, co-authored 21 publications receiving 1854 citations. Previous affiliations of Geraldine L.C. Paulus include Harvard University & RMIT University.
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Journal ArticleDOI
RNF166 Determines Recruitment of Adaptor Proteins during Antibacterial Autophagy
Robert J. Heath,Robert J. Heath,Gautam Goel,Gautam Goel,Leigh A. Baxt,Leigh A. Baxt,Jason S. Rush,Vishnu Mohanan,Vishnu Mohanan,Geraldine L.C. Paulus,Geraldine L.C. Paulus,Vijay Jani,Vijay Jani,Kara G. Lassen,Kara G. Lassen,Ramnik J. Xavier,Ramnik J. Xavier +16 more
TL;DR: In this article, the role of E3 ligases in antibacterial autophagy has been investigated and it was shown that RNF166 catalyzes K29-and K33-linked polyubiquitination of p62 at residues K91 and K189.
Journal ArticleDOI
Evolution of physical and electronic structures of bilayer graphene upon chemical functionalization.
TL;DR: The covalent and noncovalent functionalization of bilayer graphene is studied using an electrochemical process with aryl diazonium salts in the high conversion regime and Raman spectroscopic mapping and conductive atomic force microscopy are used to study the resulting changes in the physical and electronic structures.
Journal ArticleDOI
A graphene-based physiometer array for the analysis of single biological cells
Geraldine L.C. Paulus,Geraldine L.C. Paulus,Justin T. Nelson,Katherine Y. Lee,Qing Hua Wang,Qing Hua Wang,Nigel F. Reuel,Brittany R. Grassbaugh,Sebastian Kruss,Markita P. Landry,Jeon Woong Kang,Emma Vander Ende,Jingqing Zhang,Bin Mu,Ramachandra R. Dasari,Cary F. Opel,K. Dane Wittrup,Michael S. Strano +17 more
TL;DR: A nanoscale version of a micro-physiometer – a device that measures cellular metabolic activity from the local acidification rate and can differentiate immunoglobulin-producing human embryonic kidney (HEK) cells from non-IgG-producing control cells, and is extended to the detection of other analytes, e.g. dopamine.
Journal ArticleDOI
Autophagy and checkpoints for intracellular pathogen defense
TL;DR: Autophagy-dependent and autophagy -related gene-dependent pathways are essential in intracellular defense against a broad range of pathogens.
Journal ArticleDOI
Transcription factor TFEB cell-autonomously modulates susceptibility to intestinal epithelial cell injury in vivo.
Tatsuro Murano,Tatsuro Murano,Mehran Najibi,Mehran Najibi,Geraldine L.C. Paulus,Geraldine L.C. Paulus,Fatemeh Adiliaghdam,Aida Valencia-Guerrero,Martin K. Selig,Xiaofei Wang,Kate L. Jeffrey,Ramnik J. Xavier,Ramnik J. Xavier,Kara G. Lassen,Kara G. Lassen,Javier E. Irazoqui,Javier E. Irazoqui +16 more
TL;DR: This study reveals that TFEB is critical for resistance to intestinal epithelial cell injury, potentially mediated by APOA1.