Gerard Esteruelas

TL;DR: Their added-value in the development of alternative, more effective antibiotics against multi-resistant Gram-negative bacteria has been highlighted and their production methods, physicochemical characterization, and pharmacokinetics are reviewed.

TL;DR: Drug delivery systems such as biodegradable polymeric PLGA nanoparticles constitute a suitable alternative to topical eye administration, as they can improve ocular bioavailability and simultaneously reduce drug induced side effects.

TL;DR: In this article , a novel in situ gelling system able to disperse RLZ-NPs has been successfully developed as innovative neuroprotective strategy for potential topical treatment of glaucoma.

TL;DR: In this article , a nanostructured lipid carrier (NLC) loaded with Riluzole (RLZ-NLCs) was used for topical treatment of amyotrophic lateral sclerosis (ALS).

TL;DR: In this paper , Diclofenac was incorporated into biodegradable polymeric nanoparticles based on PLGA and the formulation was optimized using a factorial design approach.