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Miren Ettcheto

Researcher at University of Barcelona

Publications -  79
Citations -  3029

Miren Ettcheto is an academic researcher from University of Barcelona. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 22, co-authored 63 publications receiving 1636 citations. Previous affiliations of Miren Ettcheto include University of Coimbra & Rovira i Virgili University.

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Current Research Therapeutic Strategies for Alzheimer's Disease Treatment.

TL;DR: Fyn kinase blockers masitinib and saracatinib have proven to be efficacious in treating AD symptoms in experimental mouse models of the disease and an alternative strategy centred on the inhibition of the downstream Aβ signalling, particularly at the synapse is suggested.
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Dual-drug loaded nanoparticles of Epigallocatechin-3-gallate (EGCG)/Ascorbic acid enhance therapeutic efficacy of EGCG in a APPswe/PS1dE9 Alzheimer's disease mice model.

TL;DR: Oral treatment of APPswe/PS1dE9 mice with EGCG/AA NPs resulted in a marked increase in synapses, as judged by synaptophysin (SYP) expression, and reduction of neuroinflammation as well as amyloid &bgr; (A&b gr;) plaque burden and cortical levels of soluble and insoluble A&b Gr;(1‐42) peptide.
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Memantine for the Treatment of Dementia: A Review on its Current and Future Applications.

TL;DR: The data in preclinical studies suggests that MEM has a positive impact on improving AD brain neuropathology, as well as in preventing Aβ production, aggregation, or downstream neurotoxic consequences, in part through the blockade of extrasynaptic NMDAR.