Gilles Dietrich

TL;DR: In mice with colitis, the local release of opioids by colitogenic CD4(+) T cells led to significant reduction of inflammation-associated visceral hypersensitivity, thereby reducing abdominal pain.

TL;DR: The temporal changes of both disease-specific and nonspecific autoantibodies are consistently modified in autoimmune individuals.

TL;DR: The immediate decrease in FVIII:C inhibitory activity after IV Ig infusion indicates a direct interaction between IV Ig and the autoantibody, and the suggestion is that an idiotype- anti-idiotype mechanism must be at work.

TL;DR: Results show that CD4+ T lymphocytes acquire antinociceptive effector properties when specifically primed by Ag and point out analgesia as a property linked to the effector phase of adaptive T cell response.

TL;DR: Comparison of reactivity on a panel of self antigens of affinity‐purified anti‐DNA and anti‐thyroglobulin IgG autoantibodies from the serum of patients with systemic lupus erythematosus and autoimmune thyroiditis indicates that polyreactivity of autoantsibodies is a feature that does not allow one to distinguish between natural and disease‐associated autoantIBodies as well as between V‐region‐connected and unconnected autoant