G
Giorgio Camilloni
Researcher at Sapienza University of Rome
Publications - 54
Citations - 1297
Giorgio Camilloni is an academic researcher from Sapienza University of Rome. The author has contributed to research in topics: DNA & Saccharomyces cerevisiae. The author has an hindex of 18, co-authored 53 publications receiving 1211 citations. Previous affiliations of Giorgio Camilloni include University of Siena.
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Journal ArticleDOI
Substantial histone reduction modulates genomewide nucleosomal occupancy and global transcriptional output.
Barbara Celona,Assaf Weiner,Francesca Di Felice,Francesco M. Mancuso,Elisa Cesarini,Riccardo L. Rossi,Lorna Gregory,Dilair Baban,Grazisa Rossetti,Paolo Grianti,Massimiliano Pagani,Tiziana Bonaldi,Jiannis Ragoussis,Nir Friedman,Giorgio Camilloni,Marco Bianchi,Alessandra Agresti +16 more
TL;DR: It is suggested that variation in nucleosome number, by affecting nucleosomal occupancy both genomewide and gene-specifically, constitutes a novel layer of epigenetic regulation.
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Design, synthesis, and biological evaluation of sirtinol analogues as class III histone/protein deacetylase (Sirtuin) inhibitors.
Antonello Mai,Silvio Massa,Siva Lavu,Riccardo Pezzi,Silvia Simeoni,Rino Ragno,Francesca Romana Mariotti,Francesco Chiani,Giorgio Camilloni,David A. Sinclair +9 more
TL;DR: Both (R)- and (S)-sirtinol had similar inhibitory effects on the yeast and human enzymes, demonstrating no enantioselective inhibitory effect.
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Chromatin remodeling during Saccharomyces cerevisiae ADH2 gene activation.
TL;DR: Analysis of the distribution of nucleosomes over the Saccharomyces cerevisiae ADH2 promoter region in its chromosomal location shows that Adr1p is presumably required for destabilization of this nucleosome and for aiding the TATA-box accessibility to the transcription machinery.
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Sirtinol treatment reduces inflammation in human dermal microvascular endothelial cells.
Angela Orecchia,Claudia Scarponi,Francesca Felice,Elisa Cesarini,Simona Avitabile,Antonello Mai,Maria Luisa Mauro,Valentina Sirri,Giovanna Zambruno,Cristina Albanesi,Giorgio Camilloni,Cristina Maria Failla +11 more
TL;DR: Findings indicated that sirtuins may represent a promising therapeutic target for the treatment of inflammatory skin diseases characterized by a prominent microvessel involvement.
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ABFI contributes to the chromatin organization of Saccharomyces cerevisiae ARS1 B-domain
TL;DR: It is shown that ABFI protein acts as a boundary element of chromatin structure, by limiting the invasion by nucleosomes toward the essential A-domain, in Saccharomyces cerevisiae ARS1.