G
Giovanni Bernardini
Researcher at Sapienza University of Rome
Publications - 106
Citations - 3096
Giovanni Bernardini is an academic researcher from Sapienza University of Rome. The author has contributed to research in topics: Chemokine & Chemokine receptor. The author has an hindex of 30, co-authored 98 publications receiving 2583 citations.
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Journal ArticleDOI
The viral chemokine macrophage inflammatory protein-II is a selective Th2 chemoattractant.
Silvano Sozzani,Walter Luini,Giancarlo Bianchi,Paola Allavena,Timothy N. C. Wells,Monica Napolitano,Giovanni Bernardini,Annunciata Vecchi,Daniele D’Ambrosio,D. Mazzeo,Francesco Sinigaglia,Angela Santoni,Enrico Maggi,Sergio Romagnani,Alberto Mantovani +14 more
TL;DR: InII (vMIP-II) encoded by the KS-associated herpes virus 8 was a selective chemoattractant for T helper 2 (Th2 cells) and for monocytes, whereas it was inactive on other leukocytes, including Th1 cells, dendritic cells, and natural killer (NK) cells.
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Analysis of the role of chemokines in angiogenesis.
Giovanni Bernardini,Domenico Ribatti,Gaia Spinetti,Lucia Morbidelli,Marina Ziche,Angela Santoni,Maurizio C. Capogrossi,Monica Napolitano +7 more
TL;DR: Past and recent studies on chemokines as modulators of angiogenesis are summarized with particular emphasis on the methods currently used for the assessment of chemokine-mediated angiogenic or angiostatic responses.
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IL-1R8 is a checkpoint in NK cells regulating anti-tumour and anti-viral activity
Martina Molgora,Eduardo Bonavita,Andrea Ponzetta,Federica Riva,Marialuisa Barbagallo,Sébastien Jaillon,Branka Popović,Giovanni Bernardini,Elena Magrini,Francesca Gianni,Santiago Zelenay,Stipan Jonjić,Angela Santoni,Cecilia Garlanda,Alberto Mantovani,Alberto Mantovani +15 more
TL;DR: It is reported that IL-1R8 serves as a checkpoint for NK cell maturation and effector function and unleashes NK-cell-mediated resistance to hepatic carcinogenesis, haematogenous liver and lung metastasis, and cytomegalovirus infection.
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Identification of the CC chemokines TARC and macrophage inflammatory protein-1β as novel functional ligands for the CCR8 receptor
Giovanni Bernardini,Joseph A. Hedrick,Silvano Sozzani,Walter Luini,Gaia Spinetti,Mary Weiss,Satish Menon,Albert Zlotnik,Alberto Mantovani,Angela Santoni,Monica Napolitano +10 more
TL;DR: The pattern of CCR8 mRNA expression and the functional effects exerted by its ligand suggest that the triggering of this receptor may regulate multiple functions including activation, migration and proliferation of lymphoid cells.
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Novel Boundary Integral Formulation for Blade-Vortex Interaction Aerodynamics of Helicopter Rotors
TL;DR: In this article, a direct panel method based on a novel boundary integral formulation for the velocity potential is presented and applied to helicopter rotors experiencing blade-vortex interaction, which avoids the numerical instabilities arising in the standard direct-panel method in case of blade/wake impingement.