G
Giuseppe Masera
Researcher at University of Milano-Bicocca
Publications - 257
Citations - 11834
Giuseppe Masera is an academic researcher from University of Milano-Bicocca. The author has contributed to research in topics: Acute lymphocytic leukemia & Childhood Acute Lymphoblastic Leukemia. The author has an hindex of 54, co-authored 257 publications receiving 11248 citations. Previous affiliations of Giuseppe Masera include Mario Negri Institute for Pharmacological Research & University of Milan.
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Journal ArticleDOI
Prognostic value of minimal residual disease in acute lymphoblastic leukaemia in childhood
Jacques J.M. van Dongen,T Seriu,E. Renate Panzer-Grümayer,Andrea Biondi,M. J. Pongers-Willemse,Lilly Corral,Frank Stolz,Martin Schrappe,Giuseppe Masera,Willem Kamps,Helmuth Gadner,Elisabeth R. van Wering,Wolf-Dieter Ludwig,Giuseppe Basso,Marianne Ac de Bruijn,Giovanni Cazzaniga,Klaudia Hettinger,Anna van der Does-van den Berg,Wim C. J. Hop,Hansjörg Riehm,Claus R. Bartram +20 more
TL;DR: Monitoring patients with childhood ALL at consecutive time points gives clinically relevant insight into the effectiveness of treatment, and combined information on MRD from the first 3 months of treatment distinguishes patients with good prognoses from those with poor prognose, and this helps in decisions whether and how to modify treatment.
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Prenatal origin of acute lymphoblastic leukaemia in children
Joseph L. Wiemels,Giovanni Cazzaniga,Maria Daniotti,Osborn B. Eden,G. M. Addison,Giuseppe Masera,Vaskar Saha,Andrea Biondi,Mel Greaves +8 more
TL;DR: The findings showed that childhood acute lymphoblastic leukaemia is frequently initiated by a chromosome translocation event in utero and that a postnatal promotional event is also required.
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Outcome of treatment in children with philadelphia chromosome-positive acute lymphoblastic leukemia
Maurizio Aricò,Maria Grazia Valsecchi,Bruce M. Camitta,Martin Schrappe,J Chessells,André Baruchel,Paul S. Gaynon,Lewis B. Silverman,Gritta Janka-Schaub,Willem Kamps,C H Pui,Giuseppe Masera +11 more
TL;DR: Transplantation of bone marrow from an HLA-matched related donor is superior to other types of transplantation and to intensive chemotherapy alone in prolonging initial complete remissions and protecting patients from relapse or other adverse events.
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Minimal residual disease-directed risk stratification using real-time quantitative PCR analysis of immunoglobulin and T-cell receptor gene rearrangements in the international multicenter trial AIEOP-BFM ALL 2000 for childhood acute lymphoblastic leukemia.
Thomas Flohr,Thomas Flohr,André Schrauder,Giovanni Cazzaniga,Renate Panzer-Grümayer,V H J van der Velden,Susanna Fischer,Martin Stanulla,Giuseppe Basso,Felix Niggli,Beat W. Schäfer,Rosemary Sutton,Rolf Koehler,Martin Zimmermann,Maria Grazia Valsecchi,Helmut Gadner,Giuseppe Masera,Martin Schrappe,J. J. M. Van Dongen,Andrea Biondi,Claus R. Bartram +20 more
TL;DR: In conclusion, MRD-PCR-based stratification using stringent criteria is feasible in almost 80% of patients in an international multicenter trial.
Journal ArticleDOI
Incidence and clinical relevance of TEL/AML1 fusion genes in children with acute lymphoblastic leukemia enrolled in the German and Italian multicenter therapy trials
Arndt Borkhardt,Giovanni Cazzaniga,Susanne Viehmann,Maria Grazia Valsecchi,Wolf-Dieter Ludwig,Linda Burci,Silvia Mangioni,Martin Schrappe,Hansjörg Riehm,Fritz Lampert,Giuseppe Basso,Giuseppe Masera,Jochen Harbott,Andrea Biondi +13 more
TL;DR: The patients expressing the TEL/AML1 fusion mRNA appeared to have a better event-free survival (EFS) than the patients who lacked this chimeric product, and the need to include the molecular screening of the t(12; 21) translocation within ongoing prospective ALL trials to prove definitively its prognostic impact is reinforced.