G
Glyn Lewis
Researcher at University College London
Publications - 768
Citations - 57050
Glyn Lewis is an academic researcher from University College London. The author has contributed to research in topics: Population & Longitudinal study. The author has an hindex of 113, co-authored 734 publications receiving 49316 citations. Previous affiliations of Glyn Lewis include University College Hospital & St Bartholomew's Hospital.
Papers
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Journal ArticleDOI
245. Sertraline and its Effect on Aversive Processing: Secondary Analyses of the Panda Randomised Controlled Trial
Jolanda Malamud,Gemma Lewis,Michael Moutoussis,Larisa Duffy,Jessica K. Bone,Ramya Srinivasan,Glyn Lewis,Quentin J. M. Huys +7 more
TL;DR: This paper examined whether reinforcement learning mechanisms, specifically automatic inhibition, mediate the impact of selective serotonin reuptake inhibitors (SSRIs) in the context of a clinical trial and found that reinforcement learning can improve the performance of SSRIs.
The selective serotonin reuptake inhibitor sertraline alters learning from aversive reinforcements in patients with depression: evidence from a randomized controlled trial
Jolanda Malamud,Gemma Lewis,Michael Moutoussis,Larisa Duffy,Jessica K. Bone,Ramya Srinivasan,Glyn Lewis,Quentin J. M. Huys +7 more
TL;DR: The PANDA trial as mentioned in this paper was a randomized clinical trial in UK primary care comparing the SSRI sertraline with placebo for depression and anxiety, where participants performed an affective Go/NoGo RL task three times during the trial and computational models were used to infer reinforcement learning processes.
Journal ArticleDOI
Local understandings of PTSD and complex PTSD among health professionals working with adolescents in violent neighbourhoods of São Paulo city, Brazil
Alessandro Massazza,Juliana Feliciano de Almeida,Meaghen Quinlan-Davidson,Renata Teixeira da Silva,Delan Devakumar,Maria Fernanda Tourinho Peres,Glyn Lewis,Ligia Kiss +7 more
TL;DR: In this paper , the authors investigated local understandings of PTSD and complex PTSD among health professionals working with adolescents in violent neighbourhoods of São Paulo city, Brazil, and found that most participants knew about PTSD, but most did not know about complex PTSD.
Journal Article
Assessment and follow up of depressed patients by practice nurses was similar to care by GPs: Commentary
TL;DR: In this paper, the authors reported the psychiatric assessment results to GPs and provided a summary in the notes for 74 patients, but nurses could advise patients to report any specific problems to their GP and discussed each patient with the GP who then determined the course of treatment.
Posted ContentDOI
Meta-analysis of CYP2C19 and CYP2D6 metabolic activity on antidepressant response from 13 clinical studies
Danyang Li,Oliver Pain,Chiara Fabbri,Win Lee Edwin Wong,Christopher Lo,Stephan Ripke,Annamaria Cattaneo,Daniel Souery,Mojca Z. Dernovsek,Neven Henigsberg,Joanna Hauser,Glyn Lewis,Ole Mors,Nader Perroud,Marcella Rietschel,Rudolf Uher,Wolfgang Maier,Katherine J. Aitchison,Bernhard T. Baune,Joanna M. Biernacka,Guido Bondolfi,Katharina Domschke,Masaki Kato,Yu-Li Liu,Alessandro Serretti,Shih-Jen Tsai,Richard M. Weinshilboum,Andrew M. McIntosh,Cathryn M. Lewis +28 more
TL;DR: In this article , an individual data from 13 clinical studies of European and East Asian ancestry populations were collected, and individual data was used to translate genetic polymorphisms to four metabolic phenotypes (poor, intermediate, normal, and ultrarapid) of CYP 2C19 and CYP2D6.