Glyn Lewis

TL;DR: A systematic review and meta-analysis of antidepressant activity of anti-cytokine treatment using clinical trials of chronic inflammatory conditions where depressive symptoms were measured as a secondary outcome indicates a potentially causal role for cytokines in depression and that cytokine modulators may be novel drugs for depression in chronically inflamed subjects.

TL;DR: This large and representative survey adds considerably to the increasingly held view that the sex difference in prevalence of depression is less apparent in later middle age, and is linked to the menopause.

TL;DR: Prenatal exposure to a range of infections and inflammatory responses may be associated with risk of adult schizophrenia, and larger samples, mediation and animal models should be used to investigate whether there is a ‘sensitive period’ during development, and the effects of prenatal infections on neurodevelopment.

TL;DR: No evidence is found that MBCT with support to taper or discontinue antidepressant treatment (MBCT-TS) is superior to maintenance antidepressant treatment for the prevention of depressive relapse in individuals at risk for depressive relapse or recurrence.

TL;DR: The findings support the idea that unemployment or lack of job security increases the risk of suicide and that social and economic policies that reduce unemployment will also reduce the rate of suicide.