G
Gong Chen
Researcher at Nankai University
Publications - 177
Citations - 8709
Gong Chen is an academic researcher from Nankai University. The author has contributed to research in topics: Catalysis & Alkyl. The author has an hindex of 45, co-authored 162 publications receiving 6921 citations. Previous affiliations of Gong Chen include Kunming Institute of Zoology & Memorial Sloan Kettering Cancer Center.
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Patent
Homogeneous erythropoietin and other peptides and proteins, methods and intermediates for their preparation
Samuel J. Danishefsky,J. David Warren,Jiehao Chen,Bin Wu,Gong Chen,Qian Wan,Zhongping Tan,Cindy Kan,Yu Yuan,Zihao Hua,Krishnakumar Ranganathan,John David Trzupek +11 more
TL;DR: In this paper, isolated homogeneous polyfunctionalized proteins (e.g., erythropoietin), isolated glycopeptides, and a method for preparing polyfunctionalised peptides and/or proteins via cysteine-free native chemical ligation.
Patent
Chemical reprogramming of human glial cells into neurons for brain and spinal cord repair
TL;DR: In this article, the authors used combinations of compounds that can modify signaling via Transforming growth factor beta (TGF-β), Bone morphogenetic protein (BMP), glycogen synthase kinase 3 (GSK-3), and γ-secretase/Notch pathways.
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Palladium-catalyzed picolinamide-directed iodination of remote ortho-C−H bonds of arenes: Synthesis of tetrahydroquinolines
TL;DR: A new palladium-catalyzed picolinamide (PA)-directed ortho-iodination reaction of ε-C(sp2)−H bonds of γ-arylpropylamine substrates is reported, complementing the previously reported PA-directed electrophilic aromatic substitution approach to this transformation.
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Copper-catalyzed ortho-C(sp2)-H amination of benzamides and picolinamides with alkylamines using oxygen as a green oxidant.
TL;DR: A versatile Cu-catalyzed direct ortho-C(sp2)-H amination of benzamides and picolinamides with alkylamines withAlkylamine has been achieved and has the advantages of straightforward steps and excellent functional group compatibility.
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Nitrene-Mediated P–N Coupling Under Iron Catalysis
TL;DR: In this article, the authors proposed a method for P-N and P=N coupling for catalysis, which can be used to design and synthesize functional molecules such as bioactive compounds and organic ligands.