G
Gordon R. Bernard
Researcher at Vanderbilt University Medical Center
Publications - 366
Citations - 82519
Gordon R. Bernard is an academic researcher from Vanderbilt University Medical Center. The author has contributed to research in topics: Lung injury & Sepsis. The author has an hindex of 103, co-authored 346 publications receiving 70417 citations. Previous affiliations of Gordon R. Bernard include Vanderbilt University & Louisiana State University.
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Journal ArticleDOI
Monitoring sedation status over time in ICU patients: reliability and validity of the Richmond Agitation-Sedation Scale (RASS).
E. Wesley Ely,Brenda Truman,Ayumi Shintani,Jason W. W. Thomason,Arthur P. Wheeler,Sharon M. Gordon,Joseph Francis,Theodore Speroff,Shiva Gautam,Richard Margolin,Curtis N. Sessler,Robert S. Dittus,Gordon R. Bernard +12 more
TL;DR: This is the first sedation scale to be validated for its ability to detect changes in sedation status over consecutive days of ICU care, against constructs of level of consciousness and delirium, and correlated with the administered dose of sedative and analgesic medications.
Journal ArticleDOI
Long-Term Cognitive Impairment After Critical Illness
Pratik P. Pandharipande,Timothy D. Girard,James C. Jackson,Alessandro Morandi,Jennifer L. Thompson,Brenda T. Pun,Nathan E. Brummel,Christopher G. Hughes,Eduard E. Vasilevskis,Ayumi Shintani,Karel G.M. Moons,Sunil K. Geevarghese,Angelo E. Canonico,Ramona O. Hopkins,Gordon R. Bernard,Robert S. Dittus,Eugene Wesley Ely +16 more
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Effect of Sedation With Dexmedetomidine vs Lorazepam on Acute Brain Dysfunction in Mechanically Ventilated Patients: The MENDS Randomized Controlled Trial
Pratik P. Pandharipande,Brenda T. Pun,Daniel Herr,Mervyn Maze,Timothy D. Girard,Russell R. Miller,Ayumi Shintani,Jennifer L. Thompson,James C. Jackson,Stephen A. Deppen,Renée A. Stiles,Robert S. Dittus,Gordon R. Bernard,E. Wesley Ely +13 more
TL;DR: In mechanically ventilated ICU patients managed with individualized targeted sedation, use of a dexmedetomidine infusion resulted in more days alive without delirium or coma and more time at the targeted level of sedation than with a lorazepam infusion.
Journal ArticleDOI
Comparison of two fluid-management strategies in acute lung injury
TL;DR: Although there was no significant difference in the primary outcome of 60-day mortality, the conservative strategy of fluid management improved lung function and shortened the duration of mechanical ventilation and intensive care without increasing nonpulmonary-organ failures.
Journal ArticleDOI
An Imbalance between the Excretion of Thromboxane and Prostacyclin Metabolites in Pulmonary Hypertension
Brian W. Christman,Charles D. McPherson,John H. Newman,Gayle A. King,Gordon R. Bernard,Bertron M. Groves,James E. Loyd +6 more
TL;DR: An increase in the release of the vasoconstrictor thromboxane A2, suggesting the activation of platelets, occurs in both the primary and secondary forms of pulmonary hypertension.