Guido P. Lombardi

TL;DR: Although commonly assumed to be a modern disease, the presence of atherosclerosis in premodern human beings raises the possibility of a more basic predisposition to the disease.

TL;DR: The findings suggest that coronary atherosclerosis can be avoided in most people by achieving a lifetime with very low LDL, low blood pressure, low glucose, normal body-mass index, no smoking, and plenty of physical activity.

TL;DR: A synthesis of these findings suggests that a gene-environmental interplay is causal for atherosclerosis, whereas the speed and severity of its development are secondary to known and potentially unknown environmental factors.

TL;DR: The Horus study team extended their findings, demonstrating that atherosclerosis was prevalent among 76 ancient Egyptian mummies and among 61 mummies from each of the ancient cultures of Peru, the American Southwest, and the Aleutian Islands, to challenge the assumption that Atherosclerosis is a modern disease caused by present day risk factors.

TL;DR: Findings Probable or definite atherosclerosis was noted in 47 (34%) of 137 mummies and in all four geographical populations: 29 (38%) of 76 ancient Egyptians, 13 (25%) of 51 ancient Peruvians, two (40%) of five Ancestral Puebloans, and three (60%) ofFive Unangan hunter gatherers.