G
Guido Stoll
Researcher at University of Würzburg
Publications - 191
Citations - 10833
Guido Stoll is an academic researcher from University of Würzburg. The author has contributed to research in topics: Stroke & Ischemia. The author has an hindex of 51, co-authored 172 publications receiving 9450 citations. Previous affiliations of Guido Stoll include Ruhr University Bochum.
Papers
More filters
Journal ArticleDOI
Inflammation and Atherosclerosis Novel Insights Into Plaque Formation and Destabilization
Guido Stoll,Martin Bendszus +1 more
TL;DR: The impact of inflammation on the development of atherosclerotic plaques and their destabilization opens new avenues for treatment and the effects of statins, acetylsalicyclic acid and angiotensin-converting enzyme inhibitors on stroke prevention may be attributable to their profound anti-inflammatory actions.
Journal ArticleDOI
Targeting coagulation factor XII provides protection from pathological thrombosis in cerebral ischemia without interfering with hemostasis
Christoph Kleinschnitz,Guido Stoll,Martin Bendszus,Kai Schuh,H. U. Pauer,Peter Burfeind,Christoph Renné,David Gailani,Bernhard Nieswandt,Thomas Renné +9 more
TL;DR: As FXII appears to be instrumental in pathologic fibrin formation but dispensable for hemostasis, FXII inhibition may offer a selective and safe strategy for preventing stroke and other thromboembolic diseases.
Journal ArticleDOI
Post-stroke inhibition of induced NADPH oxidase type 4 prevents oxidative stress and neurodegeneration.
Christoph Kleinschnitz,Henrike Grund,Kirstin Wingler,Melanie E. Armitage,Emma S Jones,Manish Mittal,David Barit,Tobias Schwarz,Christian Geis,Peter Kraft,K. Barthel,Michael K. Schuhmann,Alexander M. Herrmann,Sven G. Meuth,Guido Stoll,Sabine Meurer,Anja Schrewe,Lore Becker,Valerie Gailus-Durner,Helmut Fuchs,Thomas Klopstock,Martin Hrabé de Angelis,Karin Jandeleit-Dahm,Ajay M. Shah,Norbert Weissmann,Harald H.H.W. Schmidt +25 more
TL;DR: The identification of NOx4 as a major source of oxidative stress in stroke and demonstration of dramatic protection after stroke in mice by NOX4 deletion or NOX inhibition, opens up new avenues for treatment.
Journal ArticleDOI
Degeneration and regeneration of the peripheral nervous system: from Augustus Waller's observations to neuroinflammation.
TL;DR: Similarities and differences between the PNS and CNS in terms of inflammation and microglial activation after nerve injury are discussed, and point towards progress in understanding the failure of nerve fiber regeneration in the CNS.
Journal ArticleDOI
Targeting Platelets in Acute Experimental Stroke Impact of Glycoprotein Ib, VI, and IIb/IIIa Blockade on Infarct Size, Functional Outcome, and Intracranial Bleeding
Christoph Kleinschnitz,Miroslava Pozgajova,Mirko Pham,Martin Bendszus,Bernhard Nieswandt,Guido Stoll +5 more
TL;DR: Inhibition of early steps of platelet adhesion to the ischemic endothelium and the subendothelial matrix may offer a novel and safe treatment strategy in acute stroke.