G
Guie Dong
Researcher at Charlie Norwood VA Medical Center
Publications - 6
Citations - 801
Guie Dong is an academic researcher from Charlie Norwood VA Medical Center. The author has contributed to research in topics: Autophagy & Reperfusion injury. The author has an hindex of 5, co-authored 6 publications receiving 564 citations.
Papers
More filters
Journal ArticleDOI
Autophagy in proximal tubules protects against acute kidney injury
TL;DR: The results establish a renoprotective role of tubular cell autophagy in acute kidney injury where it may interfere with cell killing mechanisms and establish a renal proximal tubule-specific Autophagy-related gene 7 knockout mouse model.
Journal ArticleDOI
Autophagy in diabetic kidney disease: regulation, pathological role and therapeutic potential
Danyi Yang,Man J. Livingston,Zhiwen Liu,Guie Dong,Ming Zhang,Jian Kang Chen,Zheng Dong,Zheng Dong +7 more
TL;DR: This review summarizes the recent findings regarding the role of autophagy in the pathogenesis of diabetic kidney disease and highlights the regulation of Autophagy by the nutrient-sensing pathways and intracellular stress signaling in this disease.
Journal ArticleDOI
Epigenetic regulation in AKI and kidney repair: mechanisms and therapeutic implications.
TL;DR: A growing body of evidence suggests that epigenetic regulation is involved in the process of acute kidney injury (AKI) and kidney repair, involving remarkable changes in histone modifications, DNA methylation and the expression of various non-coding RNAs.
Journal ArticleDOI
Hypoxia, HIF, and Associated Signaling Networks in Chronic Kidney Disease
TL;DR: An updated analysis of hypoxia response, HIF, and their associated signaling network involved in the pathogenesis of CKD is presented.
Journal ArticleDOI
DNA damage response in renal ischemia-reperfusion and ATP-depletion injury of renal tubular cells.
TL;DR: The results suggest that DDR occurs during renal ischemia-reperfusion in vivo and ATP-depletion injury in vitro, and ATM, as a sensor in the DDR, may play a cytoprotective role against tubular cell injury and death.