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Gunhild Trøen

Researcher at University of Oslo

Publications -  33
Citations -  2307

Gunhild Trøen is an academic researcher from University of Oslo. The author has contributed to research in topics: Lymphoma & Retinol. The author has an hindex of 15, co-authored 29 publications receiving 2082 citations. Previous affiliations of Gunhild Trøen include Oslo University Hospital.

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Stromal gene signatures in large-B-cell lymphomas

TL;DR: Survival after treatment of diffuse large-B-cell lymphoma is influenced by differences in immune cells, fibrosis, and angiogenesis in the tumor microenvironment, and a multivariate model created from three gene-expression signatures predicted survival both in patients who received CHOP and patients who receive R-CHOP.
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Molecular cloning and characterization of STAMP2, an androgen-regulated six transmembrane protein that is overexpressed in prostate cancer.

TL;DR: Analysis of STAMP2 expression in matched normal and tumor samples microdissected from prostate cancer specimens indicates that STAMP 2 is overexpressed in prostate cancer cells compared with normal prostate epithelial cells, and ectopic expression ofSTAMP2 in prostatecancer cells significantly increases cell growth and colony formation suggesting that STamp2 may have a role in cell proliferation.
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Genomic alterations reveal potential for higher grade transformation in follicular lymphoma and confirm parallel evolution of tumor cell clones.

TL;DR: The findings support the hypothesis of common progenitor cells in FL, as the overall frequencies of CNAs in initial and late FL biopsies showed a surprisingly stable pattern through the course of the disease.
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Prognostic value of EphA2 and EphrinA-1 in squamous cell cervical carcinoma.

TL;DR: High levels of EphA2 together with moderate to high level of E phrinA-1 protein expressions in squamous cervical carcinoma were predictive for a shorter overall survival and these proteins may be valuable prognostic markers.
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Constitutive Expression of the AP-1 Transcription Factors c-jun, junD, junB, and c-fos and the Marginal Zone B-Cell Transcription Factor Notch2 in Splenic Marginal Zone Lymphoma

TL;DR: High expression of Notch2, a transcription factor that induces marginal zone B-cell differentiation, is highly suggestive for a marginal zone A-cell origin of SMZL, and the absence of concordant high expression of the MAP kinases, the signaling cascade leading to AP-1 up-regulation, suggests autoregulation of the AP-