G
Guy Cornu
Researcher at Cliniques Universitaires Saint-Luc
Publications - 124
Citations - 4129
Guy Cornu is an academic researcher from Cliniques Universitaires Saint-Luc. The author has contributed to research in topics: Sickle cell anemia & Bone marrow. The author has an hindex of 33, co-authored 124 publications receiving 4023 citations. Previous affiliations of Guy Cornu include The Catholic University of America & Université catholique de Louvain.
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Journal ArticleDOI
Haematopoietic stem cell transplantation for sickle cell anaemia: the first 50 patients transplanted in Belgium.
Christiane Vermylen,Guy Cornu,Alina Ferster,Bénédicte Brichard,J. Ninane,Augustin Ferrant,A. Zenebergh,Pascal Maes,Catharina Dhooge,Y. Benoit,Yves Beguin,Marie-Françoise Dresse,Eric Sariban +12 more
TL;DR: Clinical manifestations of the disease, as well as disease associated haemolytic anaemia, disappeared in all successfully treated patients and Kaplan–Meier estimates of overall survival, event- free survival and disease-free survival at 11 years of the whole grafted population are 93, 82 and 85%, respectively.
Journal ArticleDOI
Hematopoietic Stem-Cell Transplantation in Globoid-Cell Leukodystrophy
William Krivit,Elsa Shapiro,Charles Peters,John E. Wagner,Guy Cornu,Joanne Kurtzberg,David A. Wenger,Edwin H. Kolodny,Marie T. Vanier,Daniel J. Loes,Kathryn E. Dusenbery,Lawrence A. Lockman +11 more
TL;DR: In the four patients with late-onset disease, the central nervous system deterioration was reversed, and in the patient with the infantile form of the disease, signs and symptoms have not appeared.
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Hydroxyurea for Treatment of Severe Sickle Cell Anemia: A Pediatric Clinical Trial
Alina Ferster,Christiane Vermylen,Guy Cornu,Marc Buyse,Francis Corazza,Christine Devalck,Pierre Fondu,Michèle Toppet,Eric Sariban +8 more
TL;DR: Treatment with HU in children and young adults with severe SCA is feasible, well-tolerated, and improves the clinical course of SCA.
Journal ArticleDOI
Allogeneic bone marrow transplantation for lysosomal storage diseases
P.M. Hoogerbrugge,Oebele F. Brouwer,Pierre Bordigoni,Guy Cornu,P. Kapaun,J. J. Ortega,Anne O'Meara,Souillet G,D. Frappaz,Stéphane Blanche,Alain Fischer,O. Ringden +11 more
TL;DR: There were significant beneficial effects of bone marrow transplantation in patients with non-neuronopathic Gaucher's disease and stabilisation of disease was observed in Patients with MPS-I and Mps-II; this potential benefit needs to be confirmed by longer follow-up.
Journal ArticleDOI
Bone marrow transplantation in five children with sickle cell anaemia.
TL;DR: Five children with severe sickle cell anaemia underwent an HLA compatible allogeneic bone marrow transplantation and in four children the engraftment was rapid and sustained and cytogenetic studies in three patients confirmed the donor origin of bone marrow cells.