G
Guy Salama
Researcher at University of Pittsburgh
Publications - 125
Citations - 8696
Guy Salama is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Repolarization & Ryanodine receptor. The author has an hindex of 47, co-authored 117 publications receiving 8235 citations. Previous affiliations of Guy Salama include University of Pennsylvania & University of Leicester.
Papers
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Journal ArticleDOI
Voltage-sensitive dyes reveal a modular organization in monkey striate cortex.
Gary G. Blasdel,Guy Salama +1 more
TL;DR: In this paper, the same pattern of ocular dominance and orientation selectivity were obtained repeatedly from the same patch of cortex using the dye merocyanine oxazolone, together with current image processing techniques.
Journal ArticleDOI
Calmodulin kinase II inhibition protects against structural heart disease
Rong Zhang,Michelle S.C. Khoo,Yuejin Wu,Yingbo Yang,Chad E. Grueter,Gemin Ni,Edward Price,William H. Thiel,Silvia Guatimosim,Silvia Guatimosim,Long-Sheng Song,Ernest C. Madu,Anisha N Shah,Tatiana A. Vishnivetskaya,James B. Atkinson,Vsevolod V. Gurevich,Guy Salama,W. J. Lederer,Roger J. Colbran,Mark E. Anderson +19 more
TL;DR: CaMKII inhibition substantially prevented maladaptive remodeling from excessive βAR stimulation and myocardial infarction, and induced balanced changes in excitation-contraction coupling that preserved baseline and βAR-stimulated physiological increases in cardiac function.
Journal ArticleDOI
Imaging cellular signals in the heart in vivo: Cardiac expression of the high-signal Ca2+ indicator GCaMP2
Yvonne Tallini,Masamichi Ohkura,Bum-Rak Choi,Guangju Ji,Keiji Imoto,Robert Doran,Jane Lee,Patricia Plan,Jason Wilson,Hong Bo Xin,Atsushi Sanbe,James Gulick,John C. Mathai,Jeffrey Robbins,Guy Salama,Junichi Nakai,Michael I. Kotlikoff +16 more
TL;DR: An improved Ca(2+) sensor, GCaMP2, its inducible expression in the mouse heart, and its use to examine signaling in heart cells in vivo are described, demonstrating that GCa MP2 will have broad utility in the dissection of numerous complex cellular interactions in mammals, in vivo.
Journal ArticleDOI
Optical Imaging of the Heart
TL;DR: A critical overview of current approaches, their contributions to the field of cardiac electrophysiology, and future directions of various optical imaging modalities as applied to cardiac physiology at organ and tissue levels is provided.
Journal ArticleDOI
Engraftment of connexin 43-expressing cells prevents post-infarct arrhythmia
Wilhelm Roell,Thorsten Lewalter,Philipp Sasse,Yvonne N. Tallini,Bum-Rak Choi,Martin Breitbach,Robert Doran,Ulrich M. Becher,Seong-min Hwang,Toktam Bostani,Julia von Maltzahn,Andreas Hofmann,Shaun Reining,Britta Eiberger,Bethann Gabris,Alexander Pfeifer,Armin Welz,Klaus Willecke,Guy Salama,Jan W. Schrickel,Michael I. Kotlikoff,Bernd K. Fleischmann +21 more
TL;DR: Engraftment of Cx43-expressing myocytes has the potential to reduce life-threatening post-infarct arrhythmias through the augmentation of intercellular coupling, suggesting autologous strategies for cardiac cell-based therapy.