H
Hai-Lan Jiang
Researcher at Jinan University
Publications - 9
Citations - 83
Hai-Lan Jiang is an academic researcher from Jinan University. The author has contributed to research in topics: Chemistry & Oxidative stress. The author has an hindex of 2, co-authored 4 publications receiving 50 citations.
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Journal ArticleDOI
The furofuran-ring selectivity, hydrogen peroxide-production and low Km value are the three elements for highly effective detoxification of aflatoxin oxidase.
TL;DR: Findings indicated that the action of AFO is oxygen-dependent and hydrogen peroxide-producing, and suggested that 8,9-unsaturated carboncarbon bond of aflatoxin B1 is the potential reactive site for AFO.
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Development of an aptasensor for the fast detection of Versicolorin A
TL;DR: In this article, a simple and sensitive label-free aptasensor was developed for the electrochemical detection of Versicolorin A (VerA), which is the first precursor in the pathway of aflatoxin B1 (AFB1) biosynthesis.
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Lethality of Zinc Oxide Nanoparticles Surpasses Conventional Zinc Oxide via Oxidative Stress, Mitochondrial Damage and Calcium Overload: A Comparative Hepatotoxicity Study
TL;DR: Zhang et al. as discussed by the authors investigated the hepatotoxicity mechanism of nano zinc oxide nanoparticles (ZnO NPs) and traditional non-nano ZnO particles and identified the differences in their toxic effects.
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Oxidative stress-related canonical pyroptosis pathway, as a target of liver toxicity triggered by zinc oxide nanoparticles.
TL;DR: Zhang et al. as mentioned in this paper revealed that zinc oxide nanoparticles (ZnO NPs) disrupted zinc homeostasis and induced oxidative stress impairment in rat liver, further causing the activation of GSDMD, promoting the leakage of inflammatory cytokines including IL-1β and IL-18.
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Aflatoxin B1 Toxicity and Protective Effects of Curcumin: Molecular Mechanisms and Clinical Implications
Chongshan Dai,Erjie Tian,Zhihui Hao,Shusheng Tang,Zhanhui Wang,Gaurav Sharma,Hai-Lan Jiang,Jianzhong Shen +7 more
TL;DR: Curcumin, a natural product with multiple therapeutic activities (e.g., anti-inflammatory, antioxidant, anticancer, and immunoregulation activities), could revise AFB1-induced harmful effects by targeting these pathways.