H
Hai Yu
Researcher at University of California, Davis
Publications - 252
Citations - 9928
Hai Yu is an academic researcher from University of California, Davis. The author has contributed to research in topics: Sialic acid & Glycan. The author has an hindex of 52, co-authored 252 publications receiving 8571 citations. Previous affiliations of Hai Yu include Northwest A&F University & University of Leeds.
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Journal ArticleDOI
A multifunctional Pasteurella multocida sialyltransferase: a powerful tool for the synthesis of sialoside libraries.
Hai Yu,Harshal A. Chokhawala,Rebekah Karpel,Hui Yu,Bingyuan Wu,Jianbo Zhang,Yingxin Zhang,Qiang Jia,Xi Chen +8 more
TL;DR: A multifunctional sialyltransferase has been cloned from Pasteurella multocida strain P-1059 and expressed in E. coli as a truncated C-terminal His6-tagged recombinant protein (tPm0188Ph).
Journal ArticleDOI
Diversity in specificity, abundance, and composition of anti-Neu5Gc antibodies in normal humans: Potential implications for disease
Vered Padler-Karavani,Hai Yu,Hongzhi Cao,Harshal A. Chokhawala,Felix Karp,Nissi Varki,Xi Chen,Ajit Varki +7 more
TL;DR: It is suggested that this ongoing antigen-antibody reaction may generate chronic inflammation, possibly contributing to the high frequency of diet-related carcinomas and other diseases in humans.
Journal Article
Relationship between microcystin in drinking water and colorectal cancer.
TL;DR: The types of drinking water are positively associated with the incidence of colorectal cancer in the study sites, and this may be related to microcystin contamination of drinkingWater.
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MicroRNA-494 Is Required for the Accumulation and Functions of Tumor-Expanded Myeloid-Derived Suppressor Cells via Targeting of PTEN
Yang Liu,Lihua Lai,Qingyun Chen,Yinjing Song,Sheng Xu,Feng Ma,Xiaojian Wang,Jianli Wang,Hai Yu,Xuetao Cao,Xuetao Cao,Qingqing Wang +11 more
TL;DR: Findings reveal that TGF-β1–induced miR-494 expression in MDSCs plays a critical role in the molecular events governing the accumulation and functions of tumor-expanded M DSCs and might be identified as a potential target in cancer therapy.
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Highly efficient chemoenzymatic synthesis of naturally occurring and non-natural α-2,6-linked sialosides: A P. damsela α-2,6- sialyltransferase with extremely flexible donor-substrate specificity
TL;DR: Sialic acids are a family of α-keto acids with a 9-carbon backbone that have been predominantly found as terminal carbohydrate units on glycoproteins and glycolipids of vertebrates or as components of capsular polysaccharides and lipooligosaccharides of pathogenic bacteria.