H
Hai Yu
Researcher at University of California, Davis
Publications - 252
Citations - 9928
Hai Yu is an academic researcher from University of California, Davis. The author has contributed to research in topics: Sialic acid & Glycan. The author has an hindex of 52, co-authored 252 publications receiving 8571 citations. Previous affiliations of Hai Yu include Northwest A&F University & University of Leeds.
Papers
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Proceedings ArticleDOI
Extremum-seeking control via sliding mode with periodic search signals
Hai Yu,Umit Ozguner +1 more
TL;DR: In this paper, the authors provide the proof of the stability of an extremum-seeking control scheme enforced by a sliding mode control strategy with periodic search signals, and the stability conditions are given for a general plant modeled as a static nonlinear map possibly cascaded with a linear dynamic block.
Journal ArticleDOI
Pasteurella multocida CMP-sialic acid synthetase and mutants of Neisseria meningitidis CMP-sialic acid synthetase with improved substrate promiscuity
TL;DR: The cloning, characterization, and substrate specificity studies of a new CSS from Pasteurella multocida strain P-1059 and a CSS from Haemophillus ducreyi with improved substrate promiscuity were reported, indicating a general approach for designing enzyme mutants with improved activity and substrate Promiscuity.
Journal ArticleDOI
Efficient chemoenzymatic synthesis of sialyl Tn-antigens and derivatives
TL;DR: An N- terminal and C-terminal truncated recombinant α2-6-sialyltransferase cloned from Photobacterium sp.
Journal ArticleDOI
Efficient chemoenzymatic synthesis of biotinylated human serum albumin-sialoglycoside conjugates containing O-acetylated sialic acids.
TL;DR: This approach provides an efficient and general protocol for preparing carbohydrate-protein conjugates containing base-sensitive groups.
Journal ArticleDOI
Polyclonal human antibodies against glycans bearing red meat-derived non-human sialic acid N-glycolylneuraminic acid are stable, reproducible, complex and vary between individuals: Total antibody levels are associated with colorectal cancer risk.
Annie N. Samraj,Kimberly A. Bertrand,Robert Luben,Zahra Khedri,Hai Yu,Dzung Nguyen,Christopher J. Gregg,Sandra Diaz,Sherilyn Sawyer,Sherilyn Sawyer,Xi Chen,Heather Eliassen,Heather Eliassen,Vered Padler-Karavani,Kana Wu,Kay-Tee Khaw,Walter C. Willett,Ajit Varki +17 more
TL;DR: The finding of a positive association of total anti-Neu5Gc antibodies with CRC risk also warrants confirmation in larger prospective studies, as these antibodies have potential as biomarkers for diseases associated with red meat consumption such as carcinomas, atherosclerosis, and type 2 diabetes.