Showing papers by "Hal E. Broxmeyer published in 2003"

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Journal Article•DOI•

Mobilization of hematopoietic progenitor cells in healthy volunteers by AMD3100, a CXCR4 antagonist.

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W. Conrad Liles¹, W. Conrad Liles², Hal E. Broxmeyer², Hal E. Broxmeyer¹, Elin Rodger², Elin Rodger¹, Brent L. Wood², Brent L. Wood¹, Kai Hübel², Kai Hübel¹, Scott Cooper¹, Scott Cooper², Giao Hangoc¹, Giao Hangoc², Gary Bridger¹, Gary Bridger², Geoffrey W. Henson¹, Geoffrey W. Henson², Gary Calandra¹, Gary Calandra², David C. Dale² - Show less +17 more•Institutions (2)

Indiana University¹, University of Washington²

15 Oct 2003-Blood

TL;DR: Findings suggest potential clinical application of AMD3100 for CD34+ cell mobilization and collection for hematopoietic stem cell transplantation.

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739 citations

Journal Article•DOI•

NF-κ B Promotes Breast Cancer Cell Migration and Metastasis by Inducing the Expression of the Chemokine Receptor CXCR4

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Gregory M. Helbig¹, Kent W. Christopherson¹, Poornima Bhat-Nakshatri¹, Suresh M. Kumar¹, Hiromitsu Kishimoto¹, Kathy D. Miller¹, Hal E. Broxmeyer, Harikrishna Nakshatri - Show less +4 more•Institutions (1)

Indiana University¹

13 Jun 2003-Journal of Biological Chemistry

TL;DR: It is demonstrated that NF-κB regulates the motility of breast cancer cells by directly up-regulating the expression of CXCR4 and the SDF-1α-mediated migration is observed with cancer cells that metastasized to the lungs.

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653 citations