S
Scott Cooper
Researcher at Indiana University
Publications - 152
Citations - 14821
Scott Cooper is an academic researcher from Indiana University. The author has contributed to research in topics: Progenitor cell & Haematopoiesis. The author has an hindex of 59, co-authored 141 publications receiving 14341 citations. Previous affiliations of Scott Cooper include Indiana University – Purdue University Indianapolis & Tokyo Medical University.
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Journal ArticleDOI
Hematopoietic reconstitution in a patient with fanconi's anemia by means of umbilical-cord blood from an hla-identical sibling
Eliane Gluckman,Hal E. Broxmeyer,Arleen D. Auerbach,Henry S. Friedman,Gordon W. Douglas,Agnès Devergie,Helene Esperou,Dominique Thierry,Gérard Socié,Pierre Lehn,Scott Cooper,Denis English,Joanne Kurtzberg,Judith Bard,Edward A. Boyse +14 more
TL;DR: It is necessary to select patients suitable for vaginal or laparoscopic mesh placement for Fanconi's anemia preoperatively on the basis of prior history and once they provide informed consent for surgery.
Journal ArticleDOI
Human umbilical cord blood as a potential source of transplantable hematopoietic stem/progenitor cells
Hal E. Broxmeyer,Gordon W. Douglas,Giao Hangoc,Scott Cooper,Judith Bard,Denis English,Margaret Arny,Lewis Thomas,Edward A. Boyse +8 more
TL;DR: It was determined that granulocyte-macrophage, erythroid, and multipotential progenitor cells remained functionally viable in cord blood untreated except for addition of anticoagulant for at least 3 days at 4 degrees C or 25 degrees C (room temperature), though not at 37 degrees C, implying that these cells could be satisfactorily studied and used or cryopreserved for therapy.
Journal ArticleDOI
Rapid mobilization of murine and human hematopoietic stem and progenitor cells with AMD3100, a CXCR4 antagonist
Hal E. Broxmeyer,Christie M. Orschell,D. Wade Clapp,Giao Hangoc,Scott Cooper,P. Artur Plett,W. Conrad Liles,Xiaxin Li,Barbara Graham-Evans,Timothy B. Campbell,Gary Calandra,Gary Bridger,David C. Dale,Edward F. Srour +13 more
TL;DR: Results support the hypothesis that the CXCL12-CXCR4 axis is involved in marrow retention of HSCs and HPCs, and demonstrate the clinical potential of AMD3100 for HSC mobilization.
Journal ArticleDOI
Mobilization of hematopoietic progenitor cells in healthy volunteers by AMD3100, a CXCR4 antagonist.
W. Conrad Liles,W. Conrad Liles,Hal E. Broxmeyer,Hal E. Broxmeyer,Elin Rodger,Elin Rodger,Brent L. Wood,Brent L. Wood,Kai Hübel,Kai Hübel,Scott Cooper,Scott Cooper,Giao Hangoc,Giao Hangoc,Gary Bridger,Gary Bridger,Geoffrey W. Henson,Geoffrey W. Henson,Gary Calandra,Gary Calandra,David C. Dale +20 more
TL;DR: Findings suggest potential clinical application of AMD3100 for CD34+ cell mobilization and collection for hematopoietic stem cell transplantation.
Journal ArticleDOI
Growth characteristics and expansion of human umbilical cord blood and estimation of its potential for transplantation in adults.
Hal E. Broxmeyer,Giao Hangoc,Scott Cooper,Raul C. Ribeiro,V Graves,Mervin C. Yoder,John E. Wagner,Saroj Vadhan-Raj,L. Benninger,P Rubinstein +9 more
TL;DR: Cord blood contains a larger number of early profile MPCs than previously recognized and that there are probably sufficient numbers of cells in a single cord blood collection to engraft an adult, suggesting in vitro expansion of cord blood stem and progenitor cells may be feasible for clinical transplantation.