H
Hamid Band
Researcher at Harvard University
Publications - 15
Citations - 1206
Hamid Band is an academic researcher from Harvard University. The author has contributed to research in topics: T-cell receptor & CD3. The author has an hindex of 11, co-authored 15 publications receiving 1196 citations. Previous affiliations of Hamid Band include Tufts University.
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Journal ArticleDOI
The tyrosine kinase regulator Cbl enhances the ubiquitination and degradation of the platelet-derived growth factor receptor α
TL;DR: It is shown that overexpression of the wild-type Cbl enhances the ligand-induced ubiquitination of the platelet-derived growth factor receptor-alpha, and the PDGFRalpha in Cbl-overexpressing cells undergoes a faster lig and-induced degradation compared with that in the control cells.
Journal ArticleDOI
Biology of the human gamma delta T-cell receptor.
Journal ArticleDOI
Human Papillomavirus Oncoprotein E6 Inactivates the Transcriptional Coactivator Human ADA3
Ajay Kumar,Yongtong Zhao,Gaoyuan Meng,Mu Sheng Zeng,Seetha Srinivasan,Laurie M. Delmolino,Qingshen Gao,Goberdhan P. Dimri,Georg F. Weber,David E. Wazer,Hamid Band,Vimla Band +11 more
TL;DR: Findings reveal a novel strategy of HPV E6-induced loss of p53 function that is independent of direct p53 degradation, and inactivation of its function may allow E6 to perturb numerous cellular pathways during HPV oncogenesis.
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Complementation of the ionizing radiation sensitivity, DNA end binding, and V(D)J recombination defects of double-strand break repair mutants by the p86 Ku autoantigen.
Nikolai V. Boubnov,Kathryn T. Hall,Zachary P. Wills,Sang Eun Lee,Dong Ming He,Damien M. Benjamin,Cheryl R. Pulaski,Hamid Band,Westley H. Reeves,Eric A. Hendrickson,David T. Weaver +10 more
TL;DR: Introduction of the Ku p86 gene, but not the p70 Ku gene, complemented the IRs, DNA end binding, and variable (diversity) joining [V(D)J)J] recombination signal and coding junction deficiencies of sxi-3.
Journal ArticleDOI
Negative regulation of Lck by Cbl ubiquitin ligase.
Navin Rao,Sachiko Miyake,Alagarsamy Lakku Reddi,Patrice Douillard,Amiya K. Ghosh,Ingrid Dodge,Pengcheng Zhou,Norvin Fernandes,Hamid Band +8 more
TL;DR: It is demonstrated that T cell receptor and CD4 coligation on human T cells results in enhanced association between Cbl and Lck, and a direct, ubiquitination-dependent, negative regulatory role of C Bl for Lck in T cells, independent of Cbl-mediated regulation of ZAP-70.