H
Hamid Safizadeh
Researcher at University of Minnesota
Publications - 11
Citations - 145
Hamid Safizadeh is an academic researcher from University of Minnesota. The author has contributed to research in topics: Overhead (computing) & Basis (linear algebra). The author has an hindex of 5, co-authored 10 publications receiving 102 citations. Previous affiliations of Hamid Safizadeh include Amirkabir University of Technology.
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Journal ArticleDOI
Functional annotation of chemical libraries across diverse biological processes
Jeff S. Piotrowski,Sheena C. Li,Raamesh Deshpande,Scott W. Simpkins,Justin Nelson,Yoko Yashiroda,Jacqueline M. Barber,Hamid Safizadeh,Erin H. Wilson,Hiroki Okada,Abraham A Gebre,Karen Kubo,Nikko P. Torres,Marissa A. LeBlanc,Kerry Andrusiak,Reika Okamoto,Mami Yoshimura,Eva DeRango-Adem,Jolanda van Leeuwen,Katsuhiko Shirahige,Anastasia Baryshnikova,Grant W. Brown,Hiroyuki Hirano,Michael Costanzo,Brenda J. Andrews,Yoshikazu Ohya,Hiroyuki Osada,Minoru Yoshida,Chad L. Myers,Charles Boone +29 more
TL;DR: This work constructed an optimized, diagnostic mutant collection that is predictive for all major yeast biological processes, and identified compounds that appear to have dual modes of action.
Journal ArticleDOI
MOSAIC: a chemical-genetic interaction data repository and web resource for exploring chemical modes of action.
Justin Nelson,Scott W. Simpkins,Hamid Safizadeh,Sheena C. Li,Jeff S. Piotrowski,Hiroyuki Hirano,Yoko Yashiroda,Hiroyuki Osada,Minoru Yoshida,Charles Boone,Chad L. Myers +10 more
TL;DR: A new high-throughput platform for mapping chemical-genetic interactions in yeast that can be scaled to screen large compound collections, and this system is applied to generate CG interaction profiles for more than 13,000 compounds, creating a public database and web interface named MOSAIC.
Posted ContentDOI
Functional Annotation of Chemical Libraries across Diverse Biological Processes
Jeff S. Piotrowski,Sheena C. Li,Raamesh Deshpande,Scott W. Simpkins,Justin Nelson,Yoko Yashiroda,Jacqueline M. Barber,Hamid Safizadeh,Erin H. Wilson,Hiroki Okada,Abraham A Gebre,Karen Kubo,Nikko P. Torres,Marissa A. LeBlanc,Kerry Andrusiak,Reika Okamoto,Mami Yoshimura,Eva DeRango-Adem,Jolanda van Leeuwen,Katsuhiko Shirahige,Anastasia Baryshnikova,Grant W. Brown,Hiroyuki Hirano,Michael Costanzo,Brenda J. Andrews,Yoshikazu Ohya,Hiroyuki Osada,Minoru Yoshida,Chad L. Myers,Charles Boone +29 more
TL;DR: A highly parallel and unbiased yeast chemical-genetic screening system involving three key components, which constructed an optimized, diagnostic mutant collection that is predictive all major yeast biological processes and predicted compound functionality.
Journal ArticleDOI
Predicting bioprocess targets of chemical compounds through integration of chemical-genetic and genetic interactions.
Scott W. Simpkins,Justin Nelson,Raamesh Deshpande,Sheena C. Li,Jeff S. Piotrowski,Erin H. Wilson,Abraham A Gebre,Hamid Safizadeh,Reika Okamoto,Mami Yoshimura,Michael Costanzo,Yoko Yashiroda,Yoshikazu Ohya,Hiroyuki Osada,Minoru Yoshida,Charles Boone,Chad L. Myers +16 more
TL;DR: The CG-TARGET method achieves similar or better accuracy while substantially improving the ability to control the false discovery rate of biological process predictions, and successfully demonstrates the use of genetic interaction networks in the high-throughput functional annotation of compounds to biological processes.
Proceedings ArticleDOI
Efficient host-independent coprocessor architecture for speech coding algorithms
TL;DR: A new hardware accelerator design has been proposed which executes macro instructions (MIs) and can handle computationally intensive loops in speech coding algorithms parallel with the main processor.