H
Harry A. Quigley
Researcher at Johns Hopkins University
Publications - 506
Citations - 72465
Harry A. Quigley is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Glaucoma & Intraocular pressure. The author has an hindex of 115, co-authored 492 publications receiving 65186 citations. Previous affiliations of Harry A. Quigley include University of Miami & Johns Hopkins University School of Medicine.
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Journal ArticleDOI
Optic nerve dynein motor protein distribution changes with intraocular pressure elevation in a rat model of glaucoma.
TL;DR: It is concluded that dynein accumulates at the ONH with experimental IOP elevation in the rat, supporting the hypothesis that disrupted axonal transport in RGC may be involved in the pathogenesis of glaucoma.
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Clinician change detection viewing longitudinal stereophotographs compared to confocal scanning laser tomography in the LSU Experimental Glaucoma (LEG) Study.
John C. Ervin,H G Lemij,Richard P. Mills,Harry A. Quigley,Hilary W. Thompson,Claude F. Burgoyne +5 more
TL;DR: In this article, the authors compared change detection by confocal scanning laser tomography (CSLT) within the LSU Experimental Glaucoma (LEG) study to expert clinicians viewing the LEG stereophotographs.
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Prevalence and significance of optic disc hemorrhage in a longitudinal study of glaucoma.
TL;DR: While the number of eyes with disc hemorrhages in this study is small, in a patient with glaucoma or ocular hypertension, disc hemorrhage appears to be associated with a greater likelihood of ongoing damage, which limits its usefulness as a screening tool for glAUcoma.
Journal Article
Descending optic nerve degeneration in primates.
TL;DR: There is a signal of injury to the cell body after axotomy, though the nature of the signal and the mechanism by which it leads to cell death are unknown.
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Diagnostic capabilities of frequency-doubling technology, scanning laser polarimetry, and nerve fiber layer photographs to distinguish glaucomatous damage.
TL;DR: Using Humphrey 24-2 test results and clinical assessment as the defining features of glaucoma, it is found that the optimal mix of sensitivity and specificity values were 84% and 100% for FDT (presence of any defect); 62% and 96% for GDx (The Number, cut-off value of 27); and, 95% and 82% for NFL photographs (pres presence of any abnormality).