H
Heinz-Ulrich G. Weier
Researcher at Lawrence Berkeley National Laboratory
Publications - 72
Citations - 3957
Heinz-Ulrich G. Weier is an academic researcher from Lawrence Berkeley National Laboratory. The author has contributed to research in topics: Fluorescence in situ hybridization & Gene mapping. The author has an hindex of 24, co-authored 72 publications receiving 3852 citations. Previous affiliations of Heinz-Ulrich G. Weier include University of California, San Francisco & University of British Columbia.
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Journal ArticleDOI
A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei
TL;DR: Analysis of DNA MTase-beta-galactosidase fusion proteins has shown that association with replication foci is mediated by a novel targeting sequence located near the N-terminus of DNAMTase.
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Functional screening of 2 Mb of human chromosome 21q22.2 in transgenic mice implicates minibrain in learning defects associated with Down syndrome
Desmond J. Smith,Mary E. Stevens,Sharmila P. Sudanagunta,Roderick T. Bronson,Michael Makhinson,Ayako M. Watabe,Thomas J. O'Dell,Jingly Fung,Heinz-Ulrich G. Weier,Jan Fang Cheng,Edward M. Rubin +10 more
TL;DR: Using Down syndrome as a model for complex trait analysis, it is sought to identify loci from chromosome 21q22.2 which, when present in an extra dose, contribute to learning abnormalities associated with Down syndrome.
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Chromosome mosaicism in human embryos.
TL;DR: To assess the stage at which mosaicism occurred in preimplantation human embryos through use of fluorescence in situ hybridization (FISH) with multiple probes, full karyotypes of blastomeres from 2- to 8-cell human embryos are obtained.
Journal ArticleDOI
Comparative chromosome painting discloses homologous segments in distantly related mammals
Harry Scherthan,Thomas Cremer,Ulfur Arnason,Heinz-Ulrich G. Weier,Antonio Lima-de-Faria,Lutz Frönicke +5 more
TL;DR: It is concluded that ZOO–FISH can be used to generate comparative chromosome maps of a large number of mammalian species.
Journal Article
Chromosome abnormalities in human arrested preimplantation embryos : a multiple-probe FISH study
TL;DR: The procedure described here offers a reliable alternative to sexing of embryos by PCR and allows simultaneous ploidy assessment and suggests that the majority of abnormally developing and arrested human embryos carry numerical chromosome abnormalities.