H
Helen E. Collins
Researcher at University of Alabama at Birmingham
Publications - 25
Citations - 623
Helen E. Collins is an academic researcher from University of Alabama at Birmingham. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 10, co-authored 16 publications receiving 478 citations. Previous affiliations of Helen E. Collins include Open University & University of Leicester.
Papers
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Journal ArticleDOI
Cardiomyocyte-Specific BMAL1 Plays Critical Roles in Metabolism, Signaling, and Maintenance of Contractile Function of the Heart:
Martin E. Young,Rachel A. Brewer,Rodrigo A. Peliciari-Garcia,Helen E. Collins,Lan He,Tana L. Birky,Bradley W. Peden,Emily G. Thompson,Billy Joe Ammons,Molly S. Bray,John C. Chatham,Adam R. Wende,Qinglin Yang,Chi Wing Chow,Tami A. Martino,Karen L. Gamble +15 more
TL;DR: Studies reveal that BMAL1 influences metabolism, signaling, and contractile function of the heart, and reveals age-onset development of dilated cardiomyopathy in CBK mice, associated with a severe reduction in life span.
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STIM1/Orai1-mediated SOCE: current perspectives and potential roles in cardiac function and pathology
TL;DR: There is now substantial evidence that STIM1-mediated SOCE plays a key role in mediating cardiomyocyte hypertrophy, both in vitro and in vivo, and there is growing support for the contribution of SOCE to Ca²⁺ overload associated with ischemia/reperfusion injury.
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Protein O-GlcNAcylation and Cardiovascular (Patho)physiology
TL;DR: The goals of this minireview are to summarize the current understanding of how changes in O-GlcNAcylation influence cardiovascular pathophysiology and to highlight the evidence that O- GlcNAc cycling is critical for normal function of the cardiovascular system.
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O-GlcNAcylation and cardiovascular disease.
TL;DR: The goal of this review is to provide an overview of some of the more recent advances in the understanding of the role O-GlcNAcylation plays in mediating cardiovascular function and disease.
Journal ArticleDOI
Stromal interaction molecule 1 is essential for normal cardiac homeostasis through modulation of ER and mitochondrial function
Helen E. Collins,Lan He,Luyun Zou,Jing Qu,Lufang Zhou,Silvio H. Litovsky,Qinglin Yang,Martin E. Young,Richard B. Marchase,John C. Chatham +9 more
TL;DR: It is demonstrated for the first time that STIM1 plays an essential role in normal cardiac function in the adult heart, which may be important for the regulation of ER and mitochondrial function.