Helen J. Eyre

TL;DR: A mouse Fc receptor, designated Fcα/μR, and its human homolog, that bind both IgM and IgA with intermediate or high affinity are described that are involved in the primary stages of the immune response to microbes.

TL;DR: In situ hybridization in murine tissues revealed expression in intestinal epithelial and lymphoid cells, and Immunohistochemistry demonstrated the human MUC13 protein on the apical membrane of both columnar and goblet cells in the gastrointestinal tract, indicative of secretion in addition to presence on the cell surface.

TL;DR: Structural homology of MUC11 with rat, mouse, and human MUC3 and human and rat MUC4/ASGP2 indicate that there is a distinct subfamily of transmembrane mucins with conserved epidermal growth factor domains, and suggests that MUC12 may be involved in epithelial cell growth regulation.

TL;DR: A study of two severely affected female patients with apparently de novo balanced X;autosome translocations, both disrupting the serine-threonine kinase 9 (STK9) gene, shows that STK9 is subject to X-inactivation in normal female somatic cells and is functionally absent in the two patients, because of preferential inactivation of the normal X.

TL;DR: SOX3 and SRY are functionally interchangeable in sex determination and support the notion that SRY evolved from SOX3 via a regulatory mutation that led to its de novo expression in the early gonad.