H
Helen L. Regnery
Researcher at Centers for Disease Control and Prevention
Publications - 17
Citations - 2691
Helen L. Regnery is an academic researcher from Centers for Disease Control and Prevention. The author has contributed to research in topics: Orthomyxoviridae & Virus. The author has an hindex of 16, co-authored 17 publications receiving 2637 citations. Previous affiliations of Helen L. Regnery include Queen Mary University of London & United States Department of Agriculture.
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Journal ArticleDOI
Characterization of an avian influenza A (H5N1) virus isolated from a child with a fatal respiratory illness.
Kanta Subbarao,Alexander Klimov,Alexander Klimov,Alexander Klimov,Jacqueline M. Katz,Jacqueline M. Katz,Jacqueline M. Katz,Helen L. Regnery,Helen L. Regnery,Helen L. Regnery,Wilina Lim,Wilina Lim,Wilina Lim,Henrietta Hall,Henrietta Hall,Henrietta Hall,Michael L. Perdue,Michael L. Perdue,Michael L. Perdue,David E. Swayne,David E. Swayne,David E. Swayne,Catherine A. Bender,Catherine A. Bender,Catherine A. Bender,Jing Huang,Jing Huang,Jing Huang,Mark L. Hemphill,Mark L. Hemphill,Mark L. Hemphill,Thomas Rowe,Thomas Rowe,Thomas Rowe,Michael W. Shaw,Michael W. Shaw,Michael W. Shaw,Xiyan Xu,Xiyan Xu,Xiyan Xu,Keiji Fukuda,Keiji Fukuda,Keiji Fukuda,Nancy Cox,Nancy Cox,Nancy Cox +45 more
TL;DR: An avian H5N1 influenza A virus was isolated from a tracheal aspirate obtained from a 3-year-old child in Hong Kong with a fatal illness consistent with influenza, causing 87.5 to 100 percent mortality in experimentally inoculated White Plymouth Rock and White Leghorn chickens.
Journal ArticleDOI
Antigenic and genetic properties of viruses linked to hemorrhagic fever with renal syndrome
Connie S. Schmaljohn,Sherman E. Hasty,Joel M. Dalrymple,James W. LeDuc,Ho Wang Lee,C.-H. von Bonsdorff,M. Brummer-Korvenkontio,Antti Vaheri,Theodore F. Tsai,Helen L. Regnery,D. Goldgaber,Pyung Woo Lee +11 more
TL;DR: Examination and comparison of eight representative isolates from endemic disease areas and from regions with no known associated HFRS indicate that these viruses represent a new and unique group that constitutes a separate genus in the Bunyaviridae family of animal viruses.
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Common Emergence of Amantadine- and Rimantadine-Resistant Influenza A Viruses in Symptomatic Immunocompromised Adults
Janet A. Englund,Richard E. Champlin,Philip R. Wyde,Hagop M. Kantarjian,Robert L. Atmar,Jeffrey J. Tarrand,Hassan Yousuf,Helen L. Regnery,Alexander Klimov,Nancy J. Cox,Estella Whimbey +10 more
TL;DR: It is concluded that development of antiviral resistance in immunocompromised individuals should be considered when they have been treated with antivirals and have shed influenza virus for a prolonged period and isolates from five of six patients were resistant.
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Antigenic and genetic characterization of the haemagglutinins of recent cocirculating strains of influenza B virus.
Abstract: The antigenic and genetic characteristics of the haemagglutinins of influenza type B viruses isolated since 1988 during periods of both widespread activity (1990/1991) and sporadic activity (1989/1990) were examined using microneutralization tests and direct RNA sequencing. During 1989/1990, influenza B viruses representative of two distinct lineages antigenically and genetically related to either B/Victoria/2/87 or B/Yamagata/16/88 were isolated, and a minor drift variant of B/Yamagata/16/88, B/Hong Kong/22/89, was identified. In 1990/1991, B/Hong Kong/22/89- or B/Yamagata/16/88-like viruses accounted for the majority of the influenza virus isolates in most countries. Sequence analysis of the HA1 domains of representative viruses confirmed the containued existence of two main lineages among recent strains of influenza B virus and identified unique amino acid changes that could account for the altered antigenic reactivity of some variants. Sequence analysis of the HA2 domains of some of the recent influenza B viruses allowed for a comparison of the evolutionary rates and patterns between the HA1 and HA2 domains.
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Influenza A among Patients with Human Immunodeficiency Virus: An Outbreak of Infection at a Residential Facility in New York City
Anne D. Fine,Carolyn B. Bridges,Angel M. De Guzman,Louise Glover,Barbara Zeller,Susan J. Wong,Inger Baker,Helen L. Regnery,Keiji Fukuda +8 more
TL;DR: HIV infection was not statistically associated with influenza-like illness (ILI) and vaccination effectiveness was similar for HIV-infected and HIV-uninfected persons, and providers should continue to offer influenza vaccination to HIV- infected persons.