H
Helle Jacobsen
Researcher at Aarhus University Hospital
Publications - 1
Citations - 529
Helle Jacobsen is an academic researcher from Aarhus University Hospital. The author has contributed to research in topics: Human leukocyte antigen & T-cell receptor. The author has an hindex of 1, co-authored 1 publications receiving 495 citations. Previous affiliations of Helle Jacobsen include University of Oxford.
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A functional and structural basis for TCR cross-reactivity in multiple sclerosis
Heather L.E. Lang,Helle Jacobsen,Helle Jacobsen,Shinji Ikemizu,Christina Andersson,Christina Andersson,Karl Harlos,Lars S. Madsen,Peter Hjorth,Leif Søndergaard,Arne Svejgaard,Kai W. Wucherpfennig,David I. Stuart,John I. Bell,E. Yvonne Jones,Lars Fugger +15 more
TL;DR: It is demonstrated that a T cell receptor from an MS patient recognized both a DRB1-restricted myelin basic protein (MBP) and DRB5*0101-restricted Epstein-Barr virus (EBV) peptide, providing structural evidence for molecular mimicry involving HLA molecules.