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Arne Svejgaard
Researcher at Copenhagen University Hospital
Publications - 91
Citations - 6858
Arne Svejgaard is an academic researcher from Copenhagen University Hospital. The author has contributed to research in topics: Human leukocyte antigen & Antigen. The author has an hindex of 38, co-authored 91 publications receiving 6753 citations. Previous affiliations of Arne Svejgaard include Lincoln's Inn & University of Oxford.
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Journal ArticleDOI
A functional and structural basis for TCR cross-reactivity in multiple sclerosis
Heather L.E. Lang,Helle Jacobsen,Helle Jacobsen,Shinji Ikemizu,Christina Andersson,Christina Andersson,Karl Harlos,Lars S. Madsen,Peter Hjorth,Leif Søndergaard,Arne Svejgaard,Kai W. Wucherpfennig,David I. Stuart,John I. Bell,E. Yvonne Jones,Lars Fugger +15 more
TL;DR: It is demonstrated that a T cell receptor from an MS patient recognized both a DRB1-restricted myelin basic protein (MBP) and DRB5*0101-restricted Epstein-Barr virus (EBV) peptide, providing structural evidence for molecular mimicry involving HLA molecules.
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Nomenclature for factors of the HLA system, 2004
Steven G.E. Marsh,E. D. Albert,Walter F. Bodmer,Ronald E. Bontrop,Bo Dupont,Henry A. Erlich,Daniel E. Geraghty,John A. Hansen,Carolyn Katovich Hurley,B. Mach,Wolfgang R. Mayr,Peter Parham,Effie W. Petersdorf,T. Sasazuki,G.M.Th. Schreuder,Jack L. Strominger,Arne Svejgaard,Paul I. Terasaki,John Trowsdale +18 more
TL;DR: The WHO Nomenclature Committee for Factors of the HLA System has decided to publish an interim report listing updated tables of alleles including those assigned since the publication of the last full report in 2002.
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HL-A Antigens and Disease Statistical and Genetical Considerations
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Histocompatibility determinants in multiple sclerosis, with special reference to clinical course
TL;DR: Family studies showed that the LD-7a character is inherited and not acquired, and the progression of the disease was significantly different from that observed in normal HL-A7 negatives.
Journal ArticleDOI
Association of mannose-binding lectin gene heterogeneity with severity of lung disease and survival in cystic fibrosis
Peter Garred,Tacjana Pressler,Hans O. Madsen,Birgitte Lidegaard Frederiksen,Arne Svejgaard,Niels Høiby,Marianne Schwartz,Christian Koch +7 more
TL;DR: Presence of MBL variant alleles is associated with poor prognosis and early death in patients with CF and the predicted age of survival was reduced by 8 years in variant allele carriers when compared with normal homozygotes.