Hendrik Wolff

TL;DR: Comparative genomics and high-resolution mass spectrometry reveal the biosynthetic gene clusters, and vast chemical diversity of natural products that they encode, in Photorhabdus and XenorhabDus, bacteria that interact with hosts as symbionts and entomopathogens.

TL;DR: It is shown that dietary tryptophan restriction (DTR) protects mice from subsequent autoimmune neuropathology challenge by altering intestinal microbiota, highlighting the potential of diet-regulated microbiota to prevent immune pathology.

TL;DR: In this article, a SAM-dependent methyltransferase was proposed to convert IPP into a variety of C6 and C7 prenyl pyrophosphates, which enabled the expansion of the terpenoid structure space beyond the borders predetermined by the isoprene rule.

TL;DR: If intense face-to-face study support was provided, the study concept proved to be feasible, despite the complexity of assessment, problems in interdisciplinary and patient communication, comorbidities, and early death from complications.

TL;DR: Local excision for patients with ycT1/2 rectal carcinomas after neoadjuvant chemoradiotherapy would, thus, miss metastases in a considerable percentage and might involve the risk of significant undertreatment in a number of patients.