H
Henk K. Koerten
Researcher at Leiden University Medical Center
Publications - 67
Citations - 5026
Henk K. Koerten is an academic researcher from Leiden University Medical Center. The author has contributed to research in topics: Stratum corneum & Corneocyte. The author has an hindex of 39, co-authored 67 publications receiving 4750 citations. Previous affiliations of Henk K. Koerten include Leiden University & University of Erlangen-Nuremberg.
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Journal ArticleDOI
Complete Polarization of Single Intestinal Epithelial Cells upon Activation of LKB1 by STRAD
Annette F. Baas,Jeroen Kuipers,Nicole N. van der Wel,Eduard Batlle,Henk K. Koerten,Peter J. Peters,Hans Clevers +6 more
TL;DR: It is concluded that LKB1 can induce complete polarity in intestinal epithelial cells, in contrast to current thinking on polarization of simple epithelia, these cells can fully polarize in the absence of junctional cell-cell contacts.
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Ultrastructure and Origin of Membrane Vesicles Associated with the Severe Acute Respiratory Syndrome Coronavirus Replication Complex
Eric J. Snijder,Yvonne van der Meer,Jessika C. Zevenhoven-Dobbe,Jos J. M. Onderwater,Jannes van der Meulen,Henk K. Koerten,A. Mieke Mommaas +6 more
TL;DR: In this article, a panel of replicase-specific antisera was used to analyze the earlier stages of severe acute respiratory syndrome coronavirus (SARS-CoV) infection in Vero E6 cells.
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Aberrant lipid organization in stratum corneum of patients with atopic dermatitis and lamellar ichthyosis.
Gonneke S. K. Pilgram,Debby C.J. Vissers,Hans van der Meulen,Henk K. Koerten,Stan Pavel,Sjan Lavrijsen,Joke A. Bouwstra +6 more
TL;DR: In atopic dermatitis stratum corneum, the presence of the hexagonal lattice (gel phase) is increased with respect to the orthorhombic packing (crystalline phase) and the results of this study suggest that the ceramide composition is important for the lateral lipid packing
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The sugar phosphotransferase system of Streptomyces coelicolor is regulated by the GntR-family regulator DasR and links N-acetylglucosamine metabolism to the control of development.
Sébastien Rigali,Harald Nothaft,Elke E. E. Noens,Elke E. E. Noens,Maximilian Schlicht,Sévrine Colson,Marisa Müller,Bernard Joris,Henk K. Koerten,David A. Hopwood,Fritz Titgemeyer,Giles P. Van Wezel +11 more
TL;DR: It is shown that high extracellular concentrations of N‐acetylglucosamine, the monomer of chitin, prevent Streptomyces coelicolor progressing beyond the vegetative state, and that this effect is absent in a mutant defective of N-acetyl glucosamines transport.
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The Production of Recombinant Infectious DI-Particles of a Murine Coronavirus in the Absence of Helper Virus
TL;DR: A system in which coronavirus-like particles can be produced and an assay to test their infectivity is developed, which is dependent on the expression of the structural proteins of MHV-A59 in the transfected cells.