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Annette F. Baas
Researcher at Utrecht University
Publications - 89
Citations - 7198
Annette F. Baas is an academic researcher from Utrecht University. The author has contributed to research in topics: Abdominal aortic aneurysm & Medicine. The author has an hindex of 33, co-authored 77 publications receiving 6147 citations. Previous affiliations of Annette F. Baas include deCODE genetics & University Medical Center Utrecht.
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Journal ArticleDOI
Long-Term Outcome of Open or Endovascular Repair of Abdominal Aortic Aneurysm
Jorg L. de Bruin,Annette F. Baas,Jaap Buth,Monique Prinssen,Ron Balm,Diederick E. Grobbee,Jan D. Blankensteijn +6 more
TL;DR: Endovascular and open repair of abdominal aortic aneurysm resulted in similar rates of survival six years after randomization, and the rate of secondary interventions was significantly higher for endovascular repair.
Journal ArticleDOI
The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm
Anna Helgadottir,Gudmar Thorleifsson,Kristinn P. Magnusson,Solveig Gretarsdottir,Valgerdur Steinthorsdottir,Andrei Manolescu,Gregory T. Jones,Gabriel J.E. Rinkel,Jan D. Blankensteijn,Antti Ronkainen,Juha Jääskeläinen,Yoshiki Kyo,Guy M. Lenk,Natzi Sakalihasan,Konstantinos Kostulas,Anders Gottsäter,Andrea Flex,Hreinn Stefansson,Torben Hansen,Gitte Andersen,Shantel Weinsheimer,Knut Borch-Johnsen,Knut Borch-Johnsen,Torben Jørgensen,Svati H. Shah,Arshed A. Quyyumi,Christopher B. Granger,Muredach P. Reilly,Harland Austin,Allan I. Levey,Viola Vaccarino,Ebba Palsdottir,G. Bragi Walters,Thorbjorg Jonsdottir,Steinunn Snorradottir,Dana Magnusdottir,Gudmundur H. Gudmundsson,Robert E. Ferrell,Sigurlaug Sveinbjörnsdóttir,Juha Hernesniemi,Juha Hernesniemi,Mika Niemelä,Raymond Limet,Karl Andersen,Gunnar Sigurdsson,Rafn Benediktsson,Eric L.G. Verhoeven,Joep A.W. Teijink,Diederick E. Grobbee,Daniel J. Rader,David A. Collier,Oluf Pedersen,Roberto Pola,Jan Hillert,Bengt Lindblad,Einar M. Valdimarsson,Hulda B Magnadottir,Cisca Wijmenga,Gerard Tromp,Annette F. Baas,Ynte M. Ruigrok,Andre M. van Rij,Helena Kuivaniemi,Janet T. Powell,Stefan E Matthiasson,Jeffrey R. Gulcher,Gudmundur Thorgeirsson,Augustine Kong,Unnur Thorsteinsdottir,Kari Stefansson +69 more
TL;DR: It is reported that rs10757278-G is associated with, in addition to CAD, abdominal aortic aneurysm (AAA) and intracranial aneurYSm, but not with T2D, and the role of this sequence variant is not confined to atherosclerotic diseases.
Journal ArticleDOI
Complete Polarization of Single Intestinal Epithelial Cells upon Activation of LKB1 by STRAD
Annette F. Baas,Jeroen Kuipers,Nicole N. van der Wel,Eduard Batlle,Henk K. Koerten,Peter J. Peters,Hans Clevers +6 more
TL;DR: It is concluded that LKB1 can induce complete polarity in intestinal epithelial cells, in contrast to current thinking on polarization of simple epithelia, these cells can fully polarize in the absence of junctional cell-cell contacts.
Journal ArticleDOI
MO25α/β interact with STRADα/β enhancing their ability to bind, activate and localize LKB1 in the cytoplasm
Jérôme Boudeau,Annette F. Baas,Maria Deak,Nick A. Morrice,Agnieszka Kieloch,Mike Schutkowski,Alan R. Prescott,Hans Clevers,Dario R. Alessi +8 more
TL;DR: It is demonstrated that the related STRADβ and MO25β isoforms are also able to stabilize LKB1 in an active complex and that it is possible to isolate complexes of L KB1 bound to STRAD andMO25 isoforms, in which the subunits are present in equimolar amounts.
Journal ArticleDOI
CHARGE syndrome: the phenotypic spectrum of mutations in the CHD7 gene
Marjolijn C.J. Jongmans,Ronald J.C. Admiraal,K. van der Donk,Lisenka E.L.M. Vissers,Annette F. Baas,Livia Kapusta,J M van Hagen,Dian Donnai,T. De Ravel,Joris A. Veltman,A. Geurts van Kessel,B. B. A. De Vries,Han G. Brunner,L. H. Hoefsloot,C M A van Ravenswaaij +14 more
TL;DR: CHD7 mutations account for the majority of the cases with CHARGE syndrome, with a broad clinical variability and without an obvious genotype-phenotype correlation.