Henning G. Kristensen

TL;DR: This study presents a meta-analysis of the phytochemical properties of seven novel drugs that have been developed over a period of several years and show promise in terms of protecting against adverse events and promoting drug safety.

TL;DR: In this article, the authors investigated the effect of three experimental parameters on the initial rate of lipolysis, whereas only the lipase activity and the concentration of bile salts and Ca(2+) affect the subsequent stages.

TL;DR: A lipolysis model was characterised and evaluated by investigating the composition of the aqueous phase and the concentration of probucol and danazol in the aQueous phase, whereby the concentrations of bile salts, fatty acids, mono-, di-, triglycerides, and drug substances were measured.

TL;DR: Differences in the physicochemical properties of the drugs resulted in differences in their distribution between the phases arising during lipolysis, resulting in variations in micellar size, lipid composition and drug concentration.

TL;DR: By using the flow-through dissolution method it was possible to obtain correlations with in vivo release of danazol under fasted and fed conditions, and both hydrodynamics and medium composition were important for the dissolution ofdanazol.