P
Patrick P. DeLuca
Researcher at University of Kentucky
Publications - 196
Citations - 9161
Patrick P. DeLuca is an academic researcher from University of Kentucky. The author has contributed to research in topics: PLGA & Drug carrier. The author has an hindex of 52, co-authored 196 publications receiving 8827 citations. Previous affiliations of Patrick P. DeLuca include Kyungsung University.
Papers
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Journal ArticleDOI
FIP/AAPS guidelines to dissolution/in vitro release testing of novel/special dosage forms
Martin Siewert,Jennifer B. Dressman,Cynthia K. Brown,Vinod P. Shah,Jean-Marc Aiache,Nobuo Aoyagi,Dennis Bashaw,Cynthia Brown,William Brown,Diane J. Burgess,John R. Crison,Patrick P. DeLuca,Ruzica Djerki,Thomas C. Foster,Kirsti Gjellan,Vivian A. Gray,Ajaz S. Hussain,Tom Ingallinera,James Klancke,Johannes Kraemer,Henning G. Kristensen,Kofi Kumi,Christian Leuner,Jobst Limberg,Petra Loos,Lenny Margulis,Patrick J. Marroum,Helga Moeller,Bernd W. Mueller,Martin Mueller-Zsigmondy,Ngozi Okafo,Larry Ouderkirk,Shravan Parsi,Saeed Qureshi,Joseph R. Robinson,Vinod P. Shah,Ramana S. Uppoor,Roger Williams +37 more
TL;DR: This study presents a meta-analysis of the phytochemical properties of seven novel drugs that have been developed over a period of several years and show promise in terms of protecting against adverse events and promoting drug safety.
Patent
Porous microspheres for drug delivery and methods for making same
TL;DR: Controlled release drug delivery systems comprised of spherical microporous polymeric network of interconnecting channels containing pore incorporated drugs or other agents wherein the drugs or agents are confined within the pore channel are described in this article.
Journal ArticleDOI
Methods to Assess in Vitro Drug Release from Injectable Polymeric Particulate Systems
Susan D’Souza,Patrick P. DeLuca +1 more
TL;DR: This review provides a compilation of the methods used to study real-time (37°C) drug release from parenteral microparticulate drug delivery systems administered via the subcutaneous or intramuscular route and criteria to aid in selection of a method are stated.
Journal ArticleDOI
Plasticizing effect of water on poly(lactide-co-glycolide).
TL;DR: It is proposed that the water responsible for plasticizing the polymer was non-freezable (bound) water and the small fraction of such water which was absorbed at high relative humidity caused polymer degradation in the same manner as bulk water.
Journal ArticleDOI
Emerging PEGylated drugs
TL;DR: PEGylation is a pharmaceutical technology that involves the covalent attachment of polyethylene glycol to a drug to improve its pharmacokinetic, pharmacodynamic, and immunological profiles, and thus, enhance its therapeutic effect.