H
Henning Stehr
Researcher at Stanford University
Publications - 73
Citations - 5350
Henning Stehr is an academic researcher from Stanford University. The author has contributed to research in topics: Lung cancer & Medicine. The author has an hindex of 21, co-authored 62 publications receiving 3561 citations.
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Journal ArticleDOI
Noninvasive Detection of BCL2, BCL6, and MYC Translocations in Diffuse Large B-Cell Lymphoma
David M. Kurtz,Florian Scherer,Aaron M. Newman,Alexander F.M. Craig,Michael C. Jin,Henning Stehr,Jacob J. Chabon,Mohammad Shahrokh Esfahani,Chih Long Liu,Li Zhou,Cynthia Glover,Brendan C. Visser,George A. Poultsides,Ranjana H. Advani,Lauren S. Maeda,Neel K. Gupta,Ronald Levy,Robert S. Ohgami,R. Eric Davis,Christian A. Kunder,Jason R. Westin,Maximilian Diehn,Ash A. Alizadeh +22 more
TL;DR: Identification of translocations from plasma without tissue samples is feasible with high sensitivity for all clinically relevant genes, and prognostic value of the method in relation to clinical outcomes is assessed.
Proceedings ArticleDOI
Increasing Clinical Trial Accrual via Automated Matching of Biomarker Criteria.
TL;DR: This study presents the development of a feature matching algorithmic pipeline that identifies patients who meet eligibility criteria of precision medicine clinical trials via genetic biomarkers and apply it to patients undergoing treatment at the Stanford Cancer Center.
Journal ArticleDOI
Development of a Dynamic Model for Personalized Risk Assessment in Large B-Cell Lymphoma
David M. Kurtz,Florian Scherer,Michael C. Jin,Joanne Soo,Alexander F.M. Craig,Mohammad Shahrokh Esfahani,Jacob J. Chabon,Henning Stehr,Chih Long Liu,Robert Tibshirani,Lauren S. Maeda,Neel K. Gupta,Michael S. Khodadoust,Ranjana H. Advani,Ronald Levy,Aaron M. Newman,Jason R. Westin,Gianluca Gaidano,Davide Rossi,Maximilian Diehn,Ash A. Alizadeh +20 more
TL;DR: Baseline and interim ctDNA measurements have prognostic significance in aggressive lymphomas and are integrated with established risk-factors to develop a model to predict an individual9s disease risk.
Journal ArticleDOI
Integrated digital error suppression for noninvasive detection of circulating tumor DNA in NSCLC.
Aaron M. Newman,Alexander F. Lovejoy,Daniel M. Klass,David M. Kurtz,Jacob J. Chabon,Florian Scherer,Henning Stehr,Chih Long Liu,Scott V. Bratman,Carmen Say,Li Zhou,Justin N. Carter,Robert B. West,George W. Sledge,Joseph B. Shrager,Billy W. Loo,Joel W. Neal,Heather A. Wakelee,Ash A. Alizadeh,Maximilian Diehn +19 more
TL;DR: This data indicates that high throughput sequencing of circulating tumor DNA (ctDNA) promises to revolutionize the detection, treatment, and monitoring of NSCLC through high throughput ctDNA sequencing is feasible and effective in low quantities.
Journal ArticleDOI
Diagnostic Impact of Next-Generation Sequencing Panels for Lymphoproliferative Neoplasms on Small-Volume Biopsies.
TL;DR: Implementation of NGS panel somatic mutation or IG/TR gene rearrangement assays on small-volume biopsies contributes to the diagnosis of LPDs in the majority of select cases for diagnostic purposes.