H
Heribert Schunkert
Researcher at Technische Universität München
Publications - 19
Citations - 1803
Heribert Schunkert is an academic researcher from Technische Universität München. The author has contributed to research in topics: Ticagrelor & Myocardial infarction. The author has an hindex of 11, co-authored 19 publications receiving 1356 citations. Previous affiliations of Heribert Schunkert include Medical University of Vienna & University of Lübeck.
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Journal ArticleDOI
Genetic Loci Associated With C-Reactive Protein Levels and Risk of Coronary Heart Disease
Paul Elliott,John C. Chambers,Weihua Zhang,Robert Clarke,J C Hopewell,John F. Peden,Jeanette Erdmann,Peter S. Braund,James C. Engert,Derrick A Bennett,Lachlan J. M. Coin,Deborah Ashby,Ioanna Tzoulaki,Ian J. Brown,Shahrul Mt-Isa,Mark I. McCarthy,Leena Peltonen,Nelson B. Freimer,Martin Farrall,Aimo Ruokonen,Anders Hamsten,Noha Lim,Philippe Froguel,Dawn Waterworth,Peter Vollenweider,Gerard Waeber,Marjo-Riitta Järvelin,Vincent Mooser,James Scott,Alistair S. Hall,Heribert Schunkert,Sonia S. Anand,Rory Collins,Nilesh J. Samani,Hugh Watkins,Jaspal S. Kooner +35 more
TL;DR: In this article, the most closely associated single-nucleotide polymorphism (SNP) in the CRP locus and published data on other CRP variants involving a total of 28,112 cases and 100,823 controls, were investigated to investigate the association of these variants with coronary heart disease.
Journal ArticleDOI
Ticagrelor or Prasugrel in Patients with Acute Coronary Syndromes.
Stefanie Schüpke,Franz-Josef Neumann,Maurizio Menichelli,Katharina Mayer,Isabell Bernlochner,Jochen Wöhrle,Gert Richardt,Christoph Liebetrau,Bernhard Witzenbichler,David Antoniucci,Ibrahim Akin,Lorenz Bott-Flügel,Marcus Fischer,Ulf Landmesser,Hugo A. Katus,Dirk Sibbing,Melchior Seyfarth,Marion Janisch,Duino Boncompagni,Raphaela Hilz,Wolfgang Rottbauer,Rainer Okrojek,Helge Möllmann,Willibald Hochholzer,Angela Migliorini,Salvatore Cassese,Pasquale Mollo,Erion Xhepa,Sebastian Kufner,Axel Strehle,Stefan Leggewie,Abdelhakim Allali,Gjin Ndrepepa,Helmut Schühlen,Dominick Angiolillo,Christian W. Hamm,Alexander Hapfelmeier,Ralph Tölg,Dietmar Trenk,Heribert Schunkert,Karl-Ludwig Laugwitz,Adnan Kastrati +41 more
TL;DR: Among patients who presented with acute coronary syndromes with or without ST-segment elevation, the incidence of death, myocardial infarction, or stroke was significantly lower among those who received prasugrel than amongThose who received ticagrelor, and the probability of major bleeding was not significantly different between the two groups.
Journal ArticleDOI
Applications and Limitations of Mouse Models for Understanding Human Atherosclerosis
Moritz von Scheidt,Yuqi Zhao,Zeyneb Kurt,Calvin Pan,Lingyao Zeng,Xia Yang,Heribert Schunkert,Aldons J. Lusis +7 more
TL;DR: Of the 46 genes with strong association signals in CAD GWASs that were studied in mouse models, all but one exhibited consistent effects on atherosclerosis-related phenotypes, and the majority were consistent between the species.
Journal ArticleDOI
Genetic markers enhance coronary risk prediction in men: the MORGAM prospective cohorts.
Maria Hughes,Olli Saarela,Jan Stritzke,Frank Kee,Kaisa Silander,Kaisa Silander,Norman Klopp,Jukka Kontto,Juha Karvanen,Christina Willenborg,Veikko Salomaa,Jarmo Virtamo,P. Amouyel,Dominique Arveiler,Jean Ferrières,Per-Gunner Wiklund,Jens Baumert,B Thorand,Patrick Diemert,David-Alexandre Trégouët,Christian Hengstenberg,Annette Peters,Alun Evans,Wolfgang Koenig,Jeanette Erdmann,Nilesh J. Samani,Kari Kuulasmaa,Heribert Schunkert +27 more
TL;DR: Genetic risk scores add precision to risk estimates for CHD and improve prediction beyond classic risk factors, particularly for middle aged men.
Genetic Markers Enhance Coronary Risk Prediction in Men: The MORGAM Prospective Cohorts
Maria Hughes,Olli Saarela,Jan Stritzke,Frank Kee,Kaisa Silander,Kaisa Silander,Norman Klopp,Jukka Kontto,Juha Karvanen,Christina Willenborg,Veikko Salomaa,Jarmo Virtamo,P. Amouyel,Dominique Arveiler,Jean Ferrières,Per-Gunner Wiklund,Jens Baumert,B Thorand,Patrick Diemert,David-Alexandre Trégouët,Christian Hengstenberg,Annette Peters,Alun Evans,Wolfgang Koenig,Jeanette Erdmann,Nilesh J. Samani,Kari Kuulasmaa,Heribert Schunkert +27 more
TL;DR: In this paper, a multilocus genetic risk score was proposed to refine coronary heart disease (CHD) prediction beyond classic risk scores and obtain more precise risk estimates using a prospective cohort design.