H
Hermann-Josef Gertz
Researcher at Leipzig University
Publications - 102
Citations - 4724
Hermann-Josef Gertz is an academic researcher from Leipzig University. The author has contributed to research in topics: Dementia & Florbetaben. The author has an hindex of 36, co-authored 101 publications receiving 4216 citations.
Papers
More filters
Journal ArticleDOI
Cerebral amyloid-β PET with florbetaben (18F) in patients with Alzheimer's disease and healthy controls: a multicentre phase 2 diagnostic study
Henryk Barthel,Hermann-Josef Gertz,Stefan Dresel,Oliver Peters,Peter Bartenstein,Katharina Buerger,Florian Hiemeyer,Sabine M Wittemer-Rump,John Seibyl,Cornelia Reininger,Osama Sabri +10 more
TL;DR: The diagnostic efficacy of the scans was established in differentiating between patients with probable disease and age-matched healthy controls on the basis of neocortical tracer uptake pattern 90-110 min post-injection and the sensitivity and specificity of florbetaben (¹⁸F) PET was assessed.
Journal ArticleDOI
A critical discussion of the role of neuroimaging in mild cognitive impairment.
TL;DR: The current neuroimaging literature is reviewed with regard to characteristic findings in mild cognitive impairment (MCI) and the possible value of Neuroimaging modalities in the prediction and early diagnosis of Alzheimer's disease (AD).
Journal ArticleDOI
Three-dimensional texture analysis of MRI brain datasets
TL;DR: The ability of the suggested 3-D texture descriptors is demonstrated on nontrivial classification tasks for pathologic findings in brain datasets, and their sensitivity and dependence on spatial image scaling are evaluated.
Journal ArticleDOI
Soluble amyloid precursor proteins in the cerebrospinal fluid as novel potential biomarkers of Alzheimer's disease: a multicenter study.
Piotr Lewczuk,Heike Kamrowski-Kruck,Oliver Peters,Isabella Heuser,Frank Jessen,Julius Popp,Katharina Bürger,Harald Hampel,Harald Hampel,Lutz Frölich,Stefanie Wolf,B Prinz,Holger Jahn,Christian Luckhaus,Robert Perneczky,Michael Hüll,Johannes Schröder,Holger Kessler,Johannes Pantel,Hermann-Josef Gertz,Hans-Wolfgang Klafki,Heike Kölsch,Udo Reulbach,Hermann Esselmann,J. M. Maler,Mirko Bibl,Johannes Kornhuber,Jens Wiltfang,Jens Wiltfang +28 more
TL;DR: In this article, the results of a multicenter study to test analytic and diagnostic performance of soluble forms of amyloid precursor proteins α and β (sAPPα and sAPPβ) in the cerebrospinal fluid (CSF) of patients with different forms of dementing conditions were presented.
Journal ArticleDOI
Hippocampal volume discriminates between normal cognition; questionable and mild dementia in the elderly
Henrike Wolf,Martin Grunwald,Frithjof Kruggel,Steffi G. Riedel-Heller,S. Angerhöfer,A Hojjatoleslami,Anke Hensel,Thomas Arendt,Hermann-Josef Gertz +8 more
TL;DR: It is concluded that hippocampal atrophy is sensitive to detect cognitive dysfunction and subjects at risk for Alzheimer's disease in the elderly population.