Hiroo Imai

TL;DR: This work identifies the ecological and molecular basis of divergent evolution in the cichlid visual system, demonstrates associated divergence in male colouration and female preferences, and shows subsequent differentiation at neutral loci, indicating reproductive isolation.

TL;DR: In addition to the recent findings on dysfunctional mutations in patients with retinitis pigmentosa or congenital night blindness, the mechanism of intramolecular signal transduction in visual pigments and their evolutionary relationship are discussed.

TL;DR: Movement of the ligand/receptor complex in rhodopsin (Rh) has been traced and it is likely that these movements involving a flip-over of the chromophoric ring trigger changes in cytoplasmic membrane loops resulting in heterotrimeric guanine nucleotide-binding protein (G protein) activation.

TL;DR: Parallel evolution in two cichlid genera under strong divergent selection in a gene that affects both is demonstrated, showing that the reciprocal fixation adapts populations to divergent light environments.

TL;DR: The results showed that the replacement of Glu-122 of rhodopsin by the residue containing green- or red-sensitive cone pigment converted rhodopin's rates of regeneration and meta II decay into those of the respective cone pigments, whereas the introduction of GLU-122 into green- sensitive cone visual pigment changed the rates of these processes into rates similar to those of r Rhodopsin.